INT62430

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Context Info
Confidence 0.32
First Reported 1996
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 4.30
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HLA-A)
Anatomy Link Frequency
macrophage 1
leucocyte 1
Anterior 1
bladder 1
A11 1
HLA-A (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 4 100.00 Very High Very High Very High
endometriosis 168 99.84 Very High Very High Very High
Neuritis 9 99.84 Very High Very High Very High
Multiple sclerosis 7 92.36 High High
Angina 1 85.92 High High
substance P 21 85.64 High High
Nerve growth factor 16 73.36 Quite High
metalloproteinase 13 72.36 Quite High
agonist 4 31.28 Quite Low
Inflammation 53 28.88 Quite Low
Disease Link Frequency Relevance Heat
Low Back Pain 4 100.00 Very High Very High Very High
Uveitis 5 99.88 Very High Very High Very High
Endometriosis 224 99.84 Very High Very High Very High
Optic Neuritis 9 99.84 Very High Very High Very High
Bladder Cancer 10 99.32 Very High Very High Very High
Cancer 13 97.48 Very High Very High Very High
Chronic Renal Failure 6 93.20 High High
Demyelinating Disease 7 92.36 High High
Left Ventricular Hypertrophy 1 90.00 High High
Necrosis 2 88.96 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Anterior uveitis with ankylosing spondylitis and HLA].
Negative_regulation (ankylosing) of HLA in Anterior associated with spinal inflammation and uveitis
1) Confidence 0.32 Published 1996 Journal Nippon Ganka Gakkai Zasshi Section Title Doc Link 8644541 Disease Relevance 0.67 Pain Relevance 0.37
Improvements in hemostasis and a decrease in human leucocyte antigen (HLA) antibodies have also been reported.
Negative_regulation (decrease) of HLA in leucocyte
2) Confidence 0.25 Published 1999 Journal Clin. Nephrol. Section Abstract Doc Link 9988140 Disease Relevance 1.09 Pain Relevance 0.09
HLA-A10 and A26 were absent in CDMS patients and A2 and A11 were significantly decreased in ON and CDMS patients.
Negative_regulation (decreased) of HLA-A10 in A11 associated with neuritis
3) Confidence 0.13 Published 2005 Journal Eur. J. Neurol. Section Abstract Doc Link 15613143 Disease Relevance 1.14 Pain Relevance 0.94
Although markers of antigen presentation on macrophages such as HLA-ABC and HLA-DR are decreased in endometriosis, macrophage-derived IL-6, IL-1?
Negative_regulation (decreased) of HLA-ABC in macrophage associated with endometriosis
4) Confidence 0.02 Published 2007 Journal Semin Immunopathol Section Body Doc Link PMC2668599 Disease Relevance 0.79 Pain Relevance 0.24
A down-regulation of HLA-ABC and beta 2-microglobulin have been reported in microdissected tumor tissue derived from bladder carcinomas [61].
Negative_regulation (regulation) of HLA-ABC in bladder associated with cancer and bladder cancer
5) Confidence 0.01 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2212656 Disease Relevance 0.61 Pain Relevance 0

General Comments

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