INT62496

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Context Info
Confidence 0.36
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 4.55
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (CSF1) cell proliferation (CSF1) extracellular space (CSF1)
extracellular region (CSF1) plasma membrane (CSF1)
Anatomy Link Frequency
granulocyte 2
macrophage 1
plasma 1
monocyte 1
CSF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 24 99.74 Very High Very High Very High
Angina 2 98.80 Very High Very High Very High
Inflammation 7 95.64 Very High Very High Very High
headache 3 87.84 High High
Pain 5 85.04 High High
psoriasis 3 66.56 Quite High
Inflammatory response 1 62.64 Quite High
alcohol 1 8.00 Low Low
imagery 2 5.72 Low Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 23 99.92 Very High Very High Very High
Necrosis 2 99.68 Very High Very High Very High
Cv General 3 Under Development 2 98.80 Very High Very High Very High
INFLAMMATION 8 95.64 Very High Very High Very High
Giant Cell Tumors 23 94.96 High High
Pressure Volume 2 Under Development 3 90.24 High High
Myelodysplastic Syndromes 3 90.04 High High
Headache 3 87.84 High High
Exanthema 3 86.88 High High
Disease 4 86.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Clinical significance of plasma concentration of macrophage colony-stimulating factor in patients with vasospastic angina].
macrophage colony-stimulating factor Binding (concentration) of in plasma associated with angina
1) Confidence 0.36 Published 2002 Journal J Cardiol Section Title Doc Link 11828794 Disease Relevance 0.19 Pain Relevance 0.28
Factors such as monocyte colony stimulating factor (m-CSF) and RANK ligand, which are important for osteoclastogenesis and for fusion of monocytes to form multinucleated giant cells, are expressed in giant cell tumors of bone[9].
m-CSF Binding (ligand) of in monocyte associated with giant cell tumors
2) Confidence 0.14 Published 2010 Journal Diagn Pathol Section Body Doc Link PMC2954972 Disease Relevance 0.70 Pain Relevance 0
Cytokines produced by immune cells (eg, RANKL, macrophage colony-stimulating factor, tumor necrosis factor alpha [TNF-?]
macrophage colony-stimulating factor Binding (immune cells) of in macrophage associated with necrosis, cancer and cytokine
3) Confidence 0.13 Published 2010 Journal Clin Interv Aging Section Body Doc Link PMC2946855 Disease Relevance 1.53 Pain Relevance 0.29
A number of cytokines are used as haemopoietic growth factors and this review focuses on toxicities associated with granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factor (G-CSF), interleukin (IL)-1, IL-3, IL-4, IL-6 and macrophage colony-stimulating factor (M-CSF).
macrophage colony-stimulating factor Binding (associated) of in granulocyte associated with cytokine
4) Confidence 0.04 Published 1995 Journal Drug Saf Section Abstract Doc Link 8652081 Disease Relevance 0.42 Pain Relevance 0.17
A number of cytokines are used as haemopoietic growth factors and this review focuses on toxicities associated with granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factor (G-CSF), interleukin (IL)-1, IL-3, IL-4, IL-6 and macrophage colony-stimulating factor (M-CSF).
M-CSF Binding (associated) of in granulocyte associated with cytokine
5) Confidence 0.03 Published 1995 Journal Drug Saf Section Abstract Doc Link 8652081 Disease Relevance 0.42 Pain Relevance 0.17
Flu-like and constitutional symptoms, sometimes dose-limiting, have been reported with IL-1, IL-3, IL-4 and IL-6, while M-CSF was occasionally associated with such adverse effects.
M-CSF Binding (associated) of
6) Confidence 0.03 Published 1995 Journal Drug Saf Section Abstract Doc Link 8652081 Disease Relevance 1.30 Pain Relevance 0.23

General Comments

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