INT62570

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Context Info
Confidence 0.48
First Reported 1996
Last Reported 2010
Negated 1
Speculated 2
Reported most in Body
Documents 48
Total Number 51
Disease Relevance 26.45
Pain Relevance 4.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pth) extracellular region (Pth) cellular_component (Pth)
Anatomy Link Frequency
parathyroid 14
blood 4
plasma 1
trabecula 1
proximal 1
Pth (Rattus norvegicus)
Pain Link Frequency Relevance Heat
headache 43 100.00 Very High Very High Very High
halothane 8 99.76 Very High Very High Very High
spondylitis 2 98.62 Very High Very High Very High
anesthesia 11 96.48 Very High Very High Very High
spinal inflammation 14 95.38 Very High Very High Very High
Pain 11 95.12 Very High Very High Very High
lumbar spondylosis 4 90.56 High High
Serotonin 6 87.44 High High
Inflammation 20 83.56 Quite High
cytokine 2 75.40 Quite High
Disease Link Frequency Relevance Heat
Headache 36 100.00 Very High Very High Very High
Hypoxia 9 99.92 Very High Very High Very High
Cardiovascular Disease 104 99.76 Very High Very High Very High
Metabolic Syndrome 65 99.76 Very High Very High Very High
Disease 59 99.74 Very High Very High Very High
Hypertension 104 99.62 Very High Very High Very High
Parathyroid Cancer 13 99.50 Very High Very High Very High
Insulin Resistance 39 99.28 Very High Very High Very High
Metastasis 7 98.72 Very High Very High Very High
Brain Injury 12 98.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effect of hypoxia on parathyroid hormone in lactating and neonatal rats: interaction with halothane.
parathyroid hormone Binding (interaction) of in parathyroid associated with hypoxia and halothane
1) Confidence 0.48 Published 2002 Journal Endocrine Section Title Doc Link 12108514 Disease Relevance 0.63 Pain Relevance 0.45
In the time frame of weeks 8 to 10, a significant interaction of PTH treatment and time was found for all structural parameters except for Conn.D, indicating that the effects of PTH were present within 2 weeks.
PTH Binding (interaction) of
2) Confidence 0.48 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2765647 Disease Relevance 0.12 Pain Relevance 0
CONCLUSION: Current literature proposes that PTH is associated with cognitive deficits.
PTH Binding (associated) of
3) Confidence 0.39 Published 2008 Journal Neurosurgery Section Body Doc Link 18728571 Disease Relevance 0 Pain Relevance 0
Over the course of weeks 8 to 14, a significant effect of time, effect of PTH treatment, and an interaction of PTH treatment and time were found for all structural parameters.
PTH Binding (interaction) of
4) Confidence 0.37 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2765647 Disease Relevance 0.14 Pain Relevance 0
PTH treatment leads to bone formation at the cleaved site, where it is most needed hereby restoring the trabecula

Prediction of gain in bone mass after PTH treatment

PTH Binding (leads) of in trabecula
5) Confidence 0.37 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2765647 Disease Relevance 0 Pain Relevance 0
It is clinically relevant to be able to predict to what extent a patient will respond to PTH in order to determine the best treatment.
PTH Binding (respond) of
6) Confidence 0.37 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2765647 Disease Relevance 0.44 Pain Relevance 0
Side localization of parathyroid adenomas was performed by venous sampling for intact parathyroid hormone (PTH) in 20 consecutive patients with primary hyperparathyroidism (pHPT) after induction of anesthesia.
PTH Binding (sampling) of in parathyroid associated with anesthesia, parathyroid cancer and hypercalcemia
7) Confidence 0.37 Published 1996 Journal World J Surg Section Abstract Doc Link 8661845 Disease Relevance 0.64 Pain Relevance 0.10
The exact etiology is unknown, but the disease is commonly associated with a high calcium-phosphorus product and elevated levels of parathyroid hormone (PTH).
parathyroid hormone Binding (associated) of in parathyroid associated with disease
8) Confidence 0.37 Published 2005 Journal Pediatr. Nephrol. Section Abstract Doc Link 16133040 Disease Relevance 1.02 Pain Relevance 0.08
The exact etiology is unknown, but the disease is commonly associated with a high calcium-phosphorus product and elevated levels of parathyroid hormone (PTH).
PTH Binding (associated) of in parathyroid associated with disease
9) Confidence 0.37 Published 2005 Journal Pediatr. Nephrol. Section Abstract Doc Link 16133040 Disease Relevance 1.02 Pain Relevance 0.08
Side localization of parathyroid adenomas was performed by venous sampling for intact parathyroid hormone (PTH) in 20 consecutive patients with primary hyperparathyroidism (pHPT) after induction of anesthesia.
parathyroid hormone Binding (sampling) of in parathyroid associated with anesthesia, parathyroid cancer and hypercalcemia
10) Confidence 0.37 Published 1996 Journal World J Surg Section Abstract Doc Link 8661845 Disease Relevance 0.64 Pain Relevance 0.10
Side localization of parathyroid adenomas by simplified intraoperative venous sampling for parathyroid hormone.
parathyroid hormone Binding (sampling) of in parathyroid associated with parathyroid cancer
11) Confidence 0.37 Published 1996 Journal World J Surg Section Title Doc Link 8661845 Disease Relevance 0.70 Pain Relevance 0.09
Over the course of weeks 8 to 14, a significant interaction of PTH treatment and time was found for all structural parameters except for Conn.D.
PTH Binding (interaction) of
12) Confidence 0.36 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2765647 Disease Relevance 0.16 Pain Relevance 0
In the time frame of weeks 8 to 10, an interaction of PTH treatment and time was found, indicating that the effects of PTH were present within 2 weeks.
PTH Binding (interaction) of
13) Confidence 0.36 Published 2009 Journal Osteoporos Int Section Body Doc Link PMC2765647 Disease Relevance 0.11 Pain Relevance 0
Fortunately, for most individuals with PTH, the headache gradually dissipates over a period of several days, weeks, or months either spontaneously or aided by non-pharmacologic and/or pharmacologic management.
PTH Binding (individuals) of associated with headache
14) Confidence 0.36 Published 2009 Journal Headache Section Abstract Doc Link 19583599 Disease Relevance 1.24 Pain Relevance 0.81
Corticosteroid hormones, parathyroid hormone, and thyroxin have all been shown to increase tooth movement.
parathyroid hormone Binding (increase) of in tooth
15) Confidence 0.36 Published 2009 Journal Am J Orthod Dentofacial Orthop Section Body Doc Link 19121496 Disease Relevance 0 Pain Relevance 0
It is associated with elevated parathyroid hormone levels and a dysregulation of the calcium/phosphate metabolism.
parathyroid hormone Binding (associated) of in parathyroid
16) Confidence 0.36 Published 2008 Journal Dermatol Clin Section Abstract Doc Link 18793990 Disease Relevance 0.71 Pain Relevance 0.10
The biological actions of PTH are mediated through binding to, at least, two distinct high affinity cell-surface receptors specific for the N-terminal and C-terminal regions of the molecule, both of which are required for normal bone metabolism.
PTH Binding (binding) of
17) Confidence 0.35 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2684083 Disease Relevance 0.25 Pain Relevance 0
Recognition of the potential role of PTH in the progression of skeletal metastases suggests novel opportunities for prostate cancer secondary prevention.
PTH Binding (Recognition) of associated with reprotox - general 1 and metastasis
18) Confidence 0.34 Published 2008 Journal Cancer Epidemiol. Biomarkers Prev. Section Abstract Doc Link 18349265 Disease Relevance 1.27 Pain Relevance 0.08
Associations of PTH with cardiovascular risk factors are presented in Table 2.
PTH Binding (Associations) of
19) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2976699 Disease Relevance 0.32 Pain Relevance 0
One previous cross sectional study found positive associations of PTH with diastolic and systolic blood pressure and with hypertension, independent of potential confounding factors and 25(OH)D.[10] In that study 25(OH)D was not associated with blood pressure variation or hypertension.
PTH Binding (associations) of in blood associated with hypertension
20) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2976699 Disease Relevance 0.72 Pain Relevance 0

General Comments

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