INT62680

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Context Info
Confidence 0.12
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.03
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KCNJ5)
KCNJ5 (Homo sapiens)
Pain Link Frequency Relevance Heat
potassium channel 3 100.00 Very High Very High Very High
Analgesic 1 25.00 Low Low
member 8 1 16.52 Low Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 32 99.36 Very High Very High Very High
Ocular Toxicity (including Many Sub-types) 1 83.52 Quite High
Diabetic Nephropathy 4 75.04 Quite High
Chronic Renal Failure 5 73.12 Quite High
Renal Disease 4 5.00 Very Low Very Low Very Low
Diabetic Retinopathy 1 5.00 Very Low Very Low Very Low
Diabetes Complications 1 5.00 Very Low Very Low Very Low
Gastric Motility Disorder 1 5.00 Very Low Very Low Very Low
Renal Failure 1 5.00 Very Low Very Low Very Low
Obesity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
From our data we conclude that the relaxant properties of amrinone, enoximone, theophylline and dipyridamole are not dependent on nitric oxide release or on interaction with KATP channels.
KATP Binding (interaction) of associated with potassium channel
1) Confidence 0.12 Published 1996 Journal Br J Anaesth Section Abstract Doc Link 8672353 Disease Relevance 0 Pain Relevance 0.10
Molecular genetic diagnosis of neonatal diabetes has a dramatic impact on diabetes therapy, because sulfonylureas bind to SUR1 subunits of the KATP channel and close the channel in an ATP-independent manner (4).
KATP Binding (bind) of associated with diabetes mellitus
2) Confidence 0.05 Published 2008 Journal Diabetes Care Section Body Doc Link PMC2571058 Disease Relevance 1.03 Pain Relevance 0

General Comments

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