INT62711

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.31
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 27
Total Number 27
Disease Relevance 15.23
Pain Relevance 2.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitosis (HGF) extracellular space (HGF) extracellular region (HGF)
cell morphogenesis (HGF)
Anatomy Link Frequency
HGF 9
hepatocyte 5
endothelial cells 2
extracellular matrix 1
HGF (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 55 100.00 Very High Very High Very High
depression 71 99.92 Very High Very High Very High
cINOD 7 99.24 Very High Very High Very High
ischemia 4 96.72 Very High Very High Very High
rheumatoid arthritis 364 95.24 Very High Very High Very High
metalloproteinase 42 93.68 High High
COX-2 inhibitor 5 88.68 High High
Pain 51 88.36 High High
intrathecal 5 87.12 High High
Pain scale 2 80.04 Quite High
Disease Link Frequency Relevance Heat
Fatigue 276 100.00 Very High Very High Very High
Depression 93 99.92 Very High Very High Very High
Hiv-narrow Range Search Term 128 99.84 Very High Very High Very High
Anxiety Disorder 53 99.56 Very High Very High Very High
INFLAMMATION 112 99.04 Very High Very High Very High
Metastasis 12 99.04 Very High Very High Very High
Stomach Cancer 19 98.56 Very High Very High Very High
Disease 167 98.44 Very High Very High Very High
Motor Neuron Diseases 198 98.36 Very High Very High Very High
Injury 25 97.48 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The hepatocyte growth factor (HGF), the first such agent that was identified as stimulating lung growth after lung resection (Yanagita et al 1993), targets both epithelial and endothelial cells.
HGF Binding (targets) of in endothelial cells
1) Confidence 0.31 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699955 Disease Relevance 0 Pain Relevance 0
The hepatocyte growth factor (HGF), the first such agent that was identified as stimulating lung growth after lung resection (Yanagita et al 1993), targets both epithelial and endothelial cells.
hepatocyte growth factor Binding (targets) of in endothelial cells
2) Confidence 0.31 Published 2007 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2699955 Disease Relevance 0 Pain Relevance 0
OBJECTIVES: Hepatocyte growth factor (HGF) is increasingly recognized for its role in a variety of hepatic and systemic diseases.
HGF Binding (recognized) of in HGF associated with disease
3) Confidence 0.29 Published 1996 Journal Am. J. Gastroenterol. Section Abstract Doc Link 8678004 Disease Relevance 0.49 Pain Relevance 0.07
Although the present data were obtained to demonstrate safety in a Phase I/early Phase II trial, the initial clinical outcome with hepatocyte growth factor gene transfer seems to indicate its usefulness as sole therapy for critical limb ischemia.
hepatocyte growth factor Binding (outcome) of in hepatocyte associated with ischemia
4) Confidence 0.25 Published 2005 Journal Expert Rev Cardiovasc Ther Section Abstract Doc Link 15889978 Disease Relevance 0.63 Pain Relevance 0.28
-catenin at Tyr654 and 670 mediated by interaction of the hepatocyte growth factor (HGF) with its cognate receptor (Met), regulates its nuclear translocation and activation [24].
hepatocyte growth factor Binding (interaction) of in HGF
5) Confidence 0.17 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2955614 Disease Relevance 0.25 Pain Relevance 0
-catenin at Tyr654 and 670 mediated by interaction of the hepatocyte growth factor (HGF) with its cognate receptor (Met), regulates its nuclear translocation and activation [24].
HGF Binding (interaction) of in HGF
6) Confidence 0.17 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2955614 Disease Relevance 0.25 Pain Relevance 0
The actions of the angiogenic factor hepatocyte growth factor (HGF) are dependent on its activation by HGF activator and binding to a specific HGF receptor.
HGF Binding (binding) of in HGF
7) Confidence 0.15 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC400438 Disease Relevance 0.83 Pain Relevance 0.27
These enzymes may play a role in angiogenesis by releasing growth factors such as FGF, VEGF and HGF that are bound to heparan sulphate in the extracellular matrix [84,129].
HGF Binding (bound) of in extracellular matrix
8) Confidence 0.15 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC400438 Disease Relevance 0.85 Pain Relevance 0.49
The actions of the angiogenic factor hepatocyte growth factor (HGF) are dependent on its activation by HGF activator and binding to a specific HGF receptor.
HGF Binding (binding) of in HGF
9) Confidence 0.15 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC400438 Disease Relevance 0.82 Pain Relevance 0.27
1, HGF, cytokines (produced by MSCs), SDF-1, RANK-L, and PGE2, as well as osteoprotegerin (OPG) interactions and indoleamine 2,3-dioxygenase (IDO) induced by INF-?
HGF Binding (interactions) of in HGF associated with cytokine
10) Confidence 0.15 Published 2010 Journal Journal of Periodontal & Implant Science Section Body Doc Link PMC3021166 Disease Relevance 0.05 Pain Relevance 0.05
It is well known that binding of hepatocyte growth factor (HGF) to its receptor (c-Met) regulates gastric cancer progression and metastasis.
hepatocyte growth factor Binding (binding) of in HGF associated with metastasis and stomach cancer
11) Confidence 0.14 Published 2001 Journal Med. Hypotheses Section Abstract Doc Link 11601879 Disease Relevance 1.00 Pain Relevance 0.07
It is well known that binding of hepatocyte growth factor (HGF) to its receptor (c-Met) regulates gastric cancer progression and metastasis.
HGF Binding (binding) of in HGF associated with metastasis and stomach cancer
12) Confidence 0.14 Published 2001 Journal Med. Hypotheses Section Abstract Doc Link 11601879 Disease Relevance 1.00 Pain Relevance 0.07
Interaction of hepatocyte growth factor and non-steroidal anti-inflammatory drugs during gastric epithelial wound healing.
hepatocyte growth factor Binding (Interaction) of in hepatocyte associated with inflammation, wound healing and cinod
13) Confidence 0.10 Published 2003 Journal Digestion Section Title Doc Link 12853723 Disease Relevance 0.29 Pain Relevance 0.14
Social functioning and vitality SF-36 domain scores had similar associations with both SF-12 physical and mental summary scores (see TableĀ 3).
SF-36 Binding (associations) of
14) Confidence 0.10 Published 2010 Journal Qual Life Res Section Body Doc Link PMC2963736 Disease Relevance 0.18 Pain Relevance 0.09
Pearson correlations were used to examine the associations of the eight SF-36 domain scores as well as the SF-36 PCS and MCS scores with SF-12 PCS and MCS scores and SF-6D scores; r2 was used to indicate the amount of shared common variance between SF-12 and SF6D with SF-36.
SF-36 Binding (associations) of
15) Confidence 0.10 Published 2010 Journal Qual Life Res Section Body Doc Link PMC2963736 Disease Relevance 0 Pain Relevance 0
Pearson correlations were used to examine the associations of the eight SF-36 domain scores as well as the SF-36 PCS and MCS scores with SF-12 PCS and MCS scores and SF-6D scores; r2 was used to indicate the amount of shared common variance between SF-12 and SF6D with SF-36.
SF-36 Binding (associations) of
16) Confidence 0.10 Published 2010 Journal Qual Life Res Section Body Doc Link PMC2963736 Disease Relevance 0 Pain Relevance 0
Binding of the natural ligand HGF to c-Met stimulates mitogenesis, motogenesis, and morphogenesis in epithelial cells [7].
HGF Binding (Binding) of in HGF
17) Confidence 0.06 Published 2008 Journal BMC Syst Biol Section Body Doc Link PMC2254585 Disease Relevance 0.49 Pain Relevance 0
Recombinant human hepatocyte growth factor (rh-HGF)
hepatocyte growth factor Binding (Recombinant) of in hepatocyte
18) Confidence 0.05 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2785861 Disease Relevance 0.67 Pain Relevance 0.08
These 3 components roughly align with the most significant scales of the SF-36, MFI and Symptom Inventory, all of which are part of the 3 inequalities we used to empirically classify illness.
SF-36 Binding (align) of associated with fatigue
19) Confidence 0.04 Published 2005 Journal BMC Med Section Body Doc Link PMC1334212 Disease Relevance 0.82 Pain Relevance 0
Further possible functions of PCI in the developing skin might involve protection from active proteases present in the amniotic fluid, such as uPA and tPA (Verkleij-Hagoort et al. 2007), or regulation of morphogen or growth factor supply in the epidermis, as PCI binds retinoids (Jerabek et al. 2001) and hepatocyte growth factor (HGF) both present in developing skin and amniotic fluid (Laurell et al. 1992; Srivastava et al. 1999).
hepatocyte growth factor Binding (binds) of in hepatocyte
20) Confidence 0.04 Published 2010 Journal J Mol Histol Section Body Doc Link PMC2852590 Disease Relevance 0.28 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox