INT62732

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Context Info
Confidence 0.45
First Reported 1993
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.27
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Nanog) nucleoplasm (Nanog) nucleolus (Nanog)
nucleus (Nanog) embryo development (Nanog) DNA binding (Nanog)
Anatomy Link Frequency
neurons 2
Nanog (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 8 100.00 Very High Very High Very High
Neuropeptide 2 75.00 Quite High
imagery 21 5.00 Very Low Very Low Very Low
Action potential 11 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
ischemia 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Teratoma 10 94.08 High High
Death 4 90.40 High High
Aids-related Complex 1 87.64 High High
Myocardial Infarction 6 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 4 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Heart Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that the synthesis of NPY, ENK and NT is enhanced in TIDA neurons during lactation and that these neuromessengers may be co-released together with DA from the ME to regulate the suckling-induced prolactin secretion at the hypothalamic and/or pituitary levels.
Positive_regulation (enhanced) of Gene_expression (synthesis) of ENK in neurons associated with enkephalin
1) Confidence 0.45 Published 1993 Journal J. Neuroendocrinol. Section Abstract Doc Link 8680430 Disease Relevance 0.09 Pain Relevance 0.63
In our microarray analysis, we observed high expression of pluripotency-related genes involved in the core hESC regulatory circuitry, including OCT4, SOX2, and NANOG, as well as CRYPTO 1 and 3, LCK, and HESX1.
Positive_regulation (high) of Gene_expression (expression) of NANOG
2) Confidence 0.16 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2565131 Disease Relevance 0.18 Pain Relevance 0

General Comments

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