INT62809

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Context Info
Confidence 0.70
First Reported 1996
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.80
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (SLC2A4) small molecule metabolic process (SLC2A4) plasma membrane (SLC2A4)
carbohydrate metabolic process (SLC2A4) transmembrane transport (SLC2A4) cytoplasm (SLC2A4)
Anatomy Link Frequency
skeletal muscle 4
SLC2A4 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 2 75.60 Quite High
tolerance 32 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammatory marker 4 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperinsulinism 4 99.36 Very High Very High Very High
Weight Loss 10 88.80 High High
Obesity 34 77.36 Quite High
Body Weight 4 61.76 Quite High
Diabetes Mellitus 86 50.00 Quite Low
Aging 38 50.00 Quite Low
Impaired Glucose Tolerance 58 5.00 Very Low Very Low Very Low
Frailty 22 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Necrosis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glucose ingestion causes GLUT4 translocation in human skeletal muscle.
Positive_regulation (causes) of Localization (translocation) of GLUT4 in skeletal muscle
1) Confidence 0.70 Published 1996 Journal Diabetes Section Title Doc Link 8690151 Disease Relevance 0 Pain Relevance 0.08
These results demonstrate that oral ingestion of glucose increases the rate of glucose transport across the plasma membrane and causes GLUT4 translocation in human skeletal muscle.
Positive_regulation (causes) of Localization (translocation) of GLUT4 in skeletal muscle
2) Confidence 0.47 Published 1996 Journal Diabetes Section Abstract Doc Link 8690151 Disease Relevance 0 Pain Relevance 0.06
Increased insulin signaling activity, along with increases in GLUT-4 protein expression, may lead to increased GLUT-4 translocation thereby increasing glucose transport and reducing insulin-resistance.
Positive_regulation (increased) of Localization (translocation) of GLUT-4 associated with hyperinsulinism
3) Confidence 0.09 Published 2011 Journal Journal of Aging Research Section Body Doc Link PMC3010636 Disease Relevance 0.40 Pain Relevance 0
Increased insulin signaling activity, along with increases in GLUT-4 protein expression, may lead to increased GLUT-4 translocation thereby increasing glucose transport and reducing insulin-resistance.
Positive_regulation (increases) of Localization (translocation) of GLUT-4 associated with hyperinsulinism
4) Confidence 0.09 Published 2011 Journal Journal of Aging Research Section Body Doc Link PMC3010636 Disease Relevance 0.40 Pain Relevance 0

General Comments

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