INT62956

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Context Info
Confidence 0.30
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CXCR2, IL8) intracellular (CXCR2, IL8) extracellular space (IL8)
extracellular region (IL8) plasma membrane (CXCR2) signal transducer activity (CXCR2)
CXCR2 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 14 96.16 Very High Very High Very High
agonist 6 91.08 High High
cINOD 2 84.08 Quite High
Potency 2 72.12 Quite High
Inflammation 2 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, IL8RA and IL8RB are both highly selective for IL-8 and have similar sequences but differ dramatically in their selectivity for all other ELR+ CXC chemokines tested.
IL8RB Positive_regulation (selective) of IL-8 associated with chemokine
1) Confidence 0.30 Published 1996 Journal J. Biol. Chem. Section Abstract Doc Link 8702798 Disease Relevance 0 Pain Relevance 0.44
Thus, IL8RA and IL8RB are both highly selective for IL-8 and have similar sequences but differ dramatically in their selectivity for all other ELR+ CXC chemokines tested.
IL8RA Positive_regulation (selective) of IL-8 associated with chemokine
2) Confidence 0.30 Published 1996 Journal J. Biol. Chem. Section Abstract Doc Link 8702798 Disease Relevance 0 Pain Relevance 0.44

General Comments

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