INT6308

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Context Info
Confidence 0.27
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HTR1D) signal transducer activity (HTR1D)
Anatomy Link Frequency
artery 2
HTR1D (Homo sapiens)
Pain Link Frequency Relevance Heat
Sumatriptan 4 99.12 Very High Very High Very High
Potency 1 90.24 High High
Migraine 1 80.20 Quite High
agonist 1 78.28 Quite High
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 1 93.00 High High
Headache 1 80.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The observations suggest that the sumatriptan-induced contraction of the dural artery is mediated via activation of 5-HT1D or 5-HT1-like receptors, whereas it does not appear to activate the 5-HT2 receptors.
Positive_regulation (mediated) of Positive_regulation (activation) of 5-HT1D in artery associated with sumatriptan
1) Confidence 0.27 Published 1992 Journal Cephalalgia Section Abstract Doc Link 1326402 Disease Relevance 0.17 Pain Relevance 0.51

General Comments

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