INT63133

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Context Info
Confidence 0.18
First Reported 1996
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 13
Total Number 13
Disease Relevance 5.31
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
shoulder 1
Pd (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 4 99.60 Very High Very High Very High
Dopamine 17 99.36 Very High Very High Very High
substance P 7 91.12 High High
Dynorphin 5 87.76 High High
imagery 42 68.36 Quite High
anesthesia 4 45.56 Quite Low
Enkephalin 2 25.00 Low Low
antagonist 2 25.00 Low Low
halothane 16 5.00 Very Low Very Low Very Low
addiction 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 596 100.00 Very High Very High Very High
Parkinson's Disease 156 100.00 Very High Very High Very High
Cognitive Disorder 20 99.36 Very High Very High Very High
Hallucination 6 98.04 Very High Very High Very High
Aids-related Complex 8 93.44 High High
Dementia 62 92.88 High High
Frontotemporal Dementia 4 91.20 High High
Vascular Dementia 9 90.40 High High
Normal Pressure Hydrocephalus 1 90.00 High High
Stroke 110 89.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Control animals of all ages had average ODIs of around 0.2 (PD25: 0.18±0.019; PD95: 0.23±0.024; PD130: 0.26±0.013, all n?
Gene_expression (0.013) of PD130
1) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518841 Disease Relevance 0 Pain Relevance 0.03
Control animals of all ages had average ODIs of around 0.2 (PD25: 0.18±0.019; PD95: 0.23±0.024; PD130: 0.26±0.013, all n?
Gene_expression (0.013) of PD25
2) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518841 Disease Relevance 0 Pain Relevance 0.03
Control animals of all ages had average ODIs of around 0.2 (PD25: 0.18±0.019; PD95: 0.23±0.024; PD130: 0.26±0.013, all n?
Gene_expression (average) of PD25
3) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518841 Disease Relevance 0 Pain Relevance 0.03
Control animals of all ages had average ODIs of around 0.2 (PD25: 0.18±0.019; PD95: 0.23±0.024; PD130: 0.26±0.013, all n?
Gene_expression (average) of PD130
4) Confidence 0.18 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2518841 Disease Relevance 0 Pain Relevance 0.03
The uncertainty in our knowledge about each of Pd, Ps, and Pl was quantified in terms of a normal distribution as this is a simple technique easily applied in different situations.
Gene_expression (each) of Pd
5) Confidence 0.06 Published 2008 Journal Emerging Infectious Diseases Section Body Doc Link PMC2609882 Disease Relevance 0.07 Pain Relevance 0
Within the PD group, 9 out of 11 patients (82%) revealed sensitivity thresholds outside the range of the control group in at least one of the four test conditions.
Gene_expression (group) of PD associated with disease
6) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440419 Disease Relevance 0.63 Pain Relevance 0
The result is noteworthy because the curvature sensitivity in absolute terms was reduced in most PD patients

Active exploration cannot overcome the loss in passive motion sensitivity in PD

Neg (cannot) Gene_expression (overcome) of PD associated with disease
7) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440419 Disease Relevance 0.56 Pain Relevance 0
This perceptual bias for convex curved curvature has been reported in earlier studies [18], [29], and we found this bias expressed in the control group as well as the PD patient group.
Gene_expression (expressed) of PD associated with disease
8) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440419 Disease Relevance 0.24 Pain Relevance 0
In the PD group, the median thresholds for detecting convex curvatures were 0.71 m?
Gene_expression (group) of PD associated with disease
9) Confidence 0.04 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2440419 Disease Relevance 0.25 Pain Relevance 0
In addition, it is likely that with SE-resistance more stabilization of the shoulder joint is needed to control the larger shoulder elevation forces, resulting in slightly increased activity levels of PD and LD.
Gene_expression (levels) of PD in shoulder
10) Confidence 0.03 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2850340 Disease Relevance 0.68 Pain Relevance 0
Sudden withdrawal can exacerbate the PD, producing, or worsening, cognitive manifestations such as hallucinations.
Gene_expression (producing) of PD associated with hallucination, cognitive disorder, disease and withdrawal
11) Confidence 0.02 Published 2010 Journal Parkinson's Disease Section Body Doc Link PMC2957227 Disease Relevance 0.73 Pain Relevance 0.05
The present study examined the modulatory role of dopamine (DA) on striatonigral preprotachykinin (PPT) and prodynorphin (PD) gene expression, employing the DA uptake inhibitor, GBR-12909 (GBR), as a tool.
Gene_expression (expression) of PD associated with dopamine
12) Confidence 0.02 Published 1996 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 8717356 Disease Relevance 0 Pain Relevance 0.43
-synuclein in PD and DLB individuals, in comparison to the AD and control groups (P?
Gene_expression (individuals) of PD associated with parkinson's disease and disease
13) Confidence 0.00 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2965495 Disease Relevance 2.16 Pain Relevance 0

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