INT63219

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Context Info
Confidence 0.76
First Reported 1996
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 1.19
Pain Relevance 1.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TDGF1P3) extracellular space (TDGF1P3) Golgi apparatus (TDGF1P3)
plasma membrane (TDGF1P3) nucleus (TDGF1P3) cytoplasm (TDGF1P3)
Anatomy Link Frequency
granulocyte 1
monocyte 1
kidney 1
neutrophils 1
TDGF1P3 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 10 99.84 Very High Very High Very High
local anesthetic 8 91.08 High High
Inflammation 8 90.84 High High
cINOD 2 49.52 Quite Low
Disease Link Frequency Relevance Heat
Adhesions 10 98.68 Very High Very High Very High
INFLAMMATION 10 90.84 High High
Bacterial Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
(b) The effect of lidocaine on the appearance of iC3b receptor (CR3) of granulocyte and monocyte (which is an important cell-adhesion-factor) was examined using flowcytometry.
Gene_expression (appearance) of CR3 in monocyte associated with lidocaine and adhesions
1) Confidence 0.76 Published 1996 Journal Masui Section Abstract Doc Link 8721131 Disease Relevance 0.10 Pain Relevance 0.65
(b) The effect of lidocaine on the appearance of iC3b receptor (CR3) of granulocyte and monocyte (which is an important cell-adhesion-factor) was examined using flowcytometry.
Gene_expression (appearance) of CR3 in granulocyte associated with lidocaine and adhesions
2) Confidence 0.26 Published 1996 Journal Masui Section Abstract Doc Link 8721131 Disease Relevance 0.10 Pain Relevance 0.65
Exposure of resting and phorbol-12-myristate-13-acetate (PMA) stimulated human neutrophils to potassium humate resulted in a decreased expression of CR3 by activated, but not resting cells, in a dose-related way.
Gene_expression (expression) of CR3 in neutrophils
3) Confidence 0.16 Published 2004 Journal Inflammation Section Abstract Doc Link 15527172 Disease Relevance 0.45 Pain Relevance 0.08
Humate also inhibited the adhesion of PMA-stimulated neutrophils to a baby hamster kidney cell line expressing ICAM1 (the CR3 ligand) (BHK331-7).
Gene_expression (expressing) of CR3 in kidney associated with adhesions
4) Confidence 0.16 Published 2004 Journal Inflammation Section Abstract Doc Link 15527172 Disease Relevance 0.54 Pain Relevance 0.11

General Comments

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