INT63230

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Context Info
Confidence 0.68
First Reported 1995
Last Reported 2009
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.50
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (GP6)
Anatomy Link Frequency
platelet 1
GP6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 87.48 High High
Dismenorea 1 86.56 High High
Disease Link Frequency Relevance Heat
Papillomavirus Infection 16 100.00 Very High Very High Very High
Acute Coronary Syndrome 9 99.56 Very High Very High Very High
Infection 3 95.96 Very High Very High Very High
Reprotox - General 1 2 94.72 High High
Pruritus 1 88.24 High High
Stable Angina Pectoris 1 87.48 High High
Non-genital Cutaneous Warts 4 86.56 High High
Coronary Artery Disease 1 83.36 Quite High
Thrombosis 1 76.76 Quite High
Adhesions 1 75.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with ACS showed significantly elevated GPVI expression levels in the first and second quartiles of platelet count compared to patients with higher platelet count [mean fluorescence intensity (MFI) +/- standard deviation): 1(st) vs. 4(th): 20.44 +/- 6.1 vs. 18.62 +/- 3.7; p=0.012; 2(nd)vs.3(rd):21.2+/-8.5vs.18.76+/-3.7;P=0.03; 2(nd)vs.4(th): 21.2+/-8.5vs.18.62+/-3.7;P=0.004], which was paralleled in trend for the CD62P expression [MFI: 1(st) vs. 4(th): 11.2 +/- 6.8 vs. 12.3 +/- 9; p=0.057; 2(nd) vs. 3(rd): 16.3 +/- 16 vs.12.7 +/- 5.3; p=0.138; 2(nd) vs. 4(th): 16.3 +/- 16 vs.11 +/- 4.4; p=0.043].
Positive_regulation (elevated) of GPVI in platelet associated with acute coronary syndrome
1) Confidence 0.68 Published 2009 Journal Thromb. Haemost. Section Abstract Doc Link 19404545 Disease Relevance 0.95 Pain Relevance 0.09
When comparing diagnostic methods for subclinical penile HPV infection, conventional histopathology appeared to be the most valuable diagnostic aid to penoscopy, while the additional use of Southern blot, in situ hybridisation and PCR assays for HPV DNA detection did not increase the predictive value of GPVI.
Neg (not) Positive_regulation (increase) of GPVI associated with papillomavirus infection and infection
2) Confidence 0.25 Published 1995 Journal Acta Derm Venereol Suppl (Stockh) Section Abstract Doc Link 8721519 Disease Relevance 1.54 Pain Relevance 0.09

General Comments

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