INT63488

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Context Info
Confidence 0.03
First Reported 1996
Last Reported 1996
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Sptan1) ligase activity (Rtcd1) cytoplasm (Sptan1)
cytosol (Sptan1) cytoskeleton (Sptan1) plasma membrane (Sptan1)
Sptan1 (Rattus norvegicus)
Rtcd1 (Mus musculus)
Pain Link Frequency Relevance Heat
MU agonist 1 99.46 Very High Very High Very High
Morphine 4 98.68 Very High Very High Very High
Opioid 1 97.80 Very High Very High Very High
agonist 4 89.48 High High
opioid receptor 3 75.00 Quite High
Dopamine 2 75.00 Quite High
adenocard 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Sprains And Strains 5 92.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In C57BL/6J mice, which are highly sensitive to morphine-induced motor stimulation, mu agonists were potent inhibitors of A2a-activated adenylyl cyclase but did not inhibit the D1-activated enzyme, while mu opioids did not inhibit A2a-activated enzyme in DBA/2J mice which show little locomotor response to morphine.
A2a Neg (not) Positive_regulation (activated) of cyclase associated with mu agonist, opioid and morphine
1) Confidence 0.03 Published 1996 Journal Brain Res. Section Abstract Doc Link 8738226 Disease Relevance 0.34 Pain Relevance 0.91

General Comments

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