INT63520

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Context Info
Confidence 0.75
First Reported 1996
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.38
Pain Relevance 1.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Homer1) cytoplasm (Homer1)
Anatomy Link Frequency
Neuronal 1
synapses 1
incisor 1
Homer1 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 11 97.92 Very High Very High Very High
Enkephalin 5 96.16 Very High Very High Very High
Nicotine 8 94.60 High High
Dynorphin 4 94.40 High High
qutenza 1 94.40 High High
addiction 3 93.60 High High
amygdala 8 86.92 High High
antagonist 4 86.76 High High
parabrachial 5 79.76 Quite High
opiate 7 75.00 Quite High
Disease Link Frequency Relevance Heat
Stress 3 81.68 Quite High
Anxiety Disorder 29 79.84 Quite High
Nociception 3 75.00 Quite High
Aids-related Complex 1 43.20 Quite Low
Targeted Disruption 4 40.32 Quite Low
Shock 15 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low
Diphtheria 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Schizophrenia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Vesl-1L regulates calcium release from RyRs and Vesl-1S reverses the effects of Vesl-1L on RyR1 and RyR2 [15,16].
Localization (release) of Vesl-1S
1) Confidence 0.75 Published 2009 Journal Mol Brain Section Body Doc Link PMC2663561 Disease Relevance 0.15 Pain Relevance 0.08
In order to investigate central pathways mediating reflex changes in cardiovascular activity, immunohistochemical localization of cells expressing the immediate-early gene, c-fos, was used to identify central nervous responding to noxious electrical stimulation of mandibular, incisor tooth dentin or chemical (capsaicin) stimulation of tooth pulp in the anesthetized rat.
Localization (localization) of immediate-early gene in incisor associated with qutenza
2) Confidence 0.23 Published 1996 Journal Brain Res. Section Abstract Doc Link 8739631 Disease Relevance 0.07 Pain Relevance 0.17
Neuronal activation was quantified by localization of (35)S-labeled probe for the immediate early gene, c-fos.
Localization (localization) of immediate early gene in Neuronal
3) Confidence 0.03 Published 2006 Journal J. Comp. Neurol. Section Abstract Doc Link 16739166 Disease Relevance 0.16 Pain Relevance 0.71
Neuronal activity-regulated pentraxin (Narp) is a secreted neuronal immediate early gene (IEG) product that regulates AMPA receptor clustering at synapses.
Localization (secreted) of early gene in synapses
4) Confidence 0.01 Published 2003 Journal Neuropsychopharmacology Section Abstract Doc Link 12784103 Disease Relevance 0 Pain Relevance 0.67

General Comments

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