INT63588

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Context Info
Confidence 0.31
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Got1) biosynthetic process (Got1) cellular amino acid metabolic process (Got1)
lysosome (Got1) cytoplasm (Got1)
Aap (Mus musculus)
Got1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 10 100.00 Very High Very High Very High
Glutamate 2 98.56 Very High Very High Very High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Injury 2 94.76 High High
Hepatitis 4 90.88 High High
Hepatotoxicity 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While AAP caused a 117-fold elevation of serum transaminase activities in mice kept on a standard laboratory diet, which was significantly exacerbated by ethanol and inhibited by nicotinic acid amide (NAA), adverse effects were noted in animals fed a diet free of precursors of NAD.
AAP Positive_regulation (caused) of Positive_regulation (elevation) of transaminase associated with paracetamol
1) Confidence 0.31 Published 1996 Journal Gen. Pharmacol. Section Abstract Doc Link 8742498 Disease Relevance 0.60 Pain Relevance 0.79

General Comments

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