INT63765

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Context Info
Confidence 0.09
First Reported 1995
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.69
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (Add3) plasma membrane (Add3) cytoskeleton (Add3)
cytoplasm (Add3)
Anatomy Link Frequency
Muller cells 1
Neuro-2a 1
Add3 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropeptide 2 99.90 Very High Very High Very High
qutenza 3 99.30 Very High Very High Very High
dorsal root ganglion 1 83.28 Quite High
Calcitonin gene-related peptide 1 79.32 Quite High
Central nervous system 18 78.28 Quite High
substance P 1 78.00 Quite High
Inflammatory response 1 75.04 Quite High
Nerve growth factor 5 75.00 Quite High
glial activation 2 69.24 Quite High
Neuritis 1 17.76 Low Low
Disease Link Frequency Relevance Heat
Shock 4 96.08 Very High Very High Very High
Sprains And Strains 41 86.96 High High
Targeted Disruption 4 85.00 Quite High
Ganglion Cysts 6 83.28 Quite High
INFLAMMATION 1 75.04 Quite High
Injury 48 63.44 Quite High
Neuroblastoma 3 50.00 Quite Low
Apoptosis 14 48.64 Quite Low
Neuritis 1 17.76 Low Low
Wound Healing 25 7.60 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In null mutants, capsaicin sensitivity, and neuropeptide and cytoskeletal protein expression were unaffected by the loss of Oct-2 expression.
Gene_expression (expression) of cytoskeletal protein associated with qutenza and neuropeptide
1) Confidence 0.09 Published 1995 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 8750882 Disease Relevance 0.24 Pain Relevance 0.60
Cytoskeletal protein expression was down- regulated in Neuro-2a-Ng cells
Gene_expression (expression) of Cytoskeletal protein in Neuro-2a
2) Confidence 0.04 Published 2007 Journal International Journal of Biological Sciences Section Body Doc Link PMC1865092 Disease Relevance 0.10 Pain Relevance 0
GFAP is a cytoskeletal protein normally expressed by astrocytes and the end-feet of Muller cells.
Gene_expression (expressed) of cytoskeletal protein in Muller cells
3) Confidence 0.02 Published 2007 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2759132 Disease Relevance 0.35 Pain Relevance 0.07

General Comments

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