INT63845

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Context Info
Confidence 0.36
First Reported 1996
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.23
Pain Relevance 1.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein targeting (Gphn) plasma membrane (Gphn) cytoskeleton (Gphn)
intracellular (Gphn) protein binding, bridging (Gphn) cytoplasm (Gphn)
Anatomy Link Frequency
skeletal muscle 2
nucleus 2
spinal cord neurons 2
Gphn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 11 100.00 Very High Very High Very High
amygdala 62 99.36 Very High Very High Very High
Spinal cord 2 97.20 Very High Very High Very High
agonist 7 90.40 High High
gABA 22 89.56 High High
Central nervous system 2 89.52 High High
Cannabinoid 5 88.68 High High
tetrodotoxin 5 68.80 Quite High
antagonist 2 57.56 Quite High
hyperexcitability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 122 98.32 Very High Very High Very High
Neuroblastoma 1 50.08 Quite High
Stress 42 50.00 Quite Low
Glioma 1 49.44 Quite Low
Post-traumatic Stress Disorder 16 5.00 Very Low Very Low Very Low
Shock 7 5.00 Very Low Very Low Very Low
Cognitive Disorder 6 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Phobia 3 5.00 Very Low Very Low Very Low
Overactive Bladder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Modulation of glycine receptor subunits and gephyrin expression in the rat facial nucleus after axotomy.
Regulation (Modulation) of Gene_expression (expression) of gephyrin in nucleus
1) Confidence 0.36 Published 2005 Journal Eur. J. Neurosci. Section Title Doc Link 15733085 Disease Relevance 0 Pain Relevance 0.07
The effects of chronic strychnine treatment on the expression and cellular distribution of gephyrin and glycine receptor were therefore tested using primary cultures of spinal cord neurons.
Regulation (effects) of Gene_expression (expression) of gephyrin in spinal cord neurons associated with spinal cord
2) Confidence 0.17 Published 1998 Journal J. Cell. Sci. Section Abstract Doc Link 9427682 Disease Relevance 0 Pain Relevance 0.09
The proportion of gephyrin and glycine receptor-immunoreactive (IR) cells was unaffected by strychnine treatment.
Neg (unaffected) Regulation (unaffected) of Gene_expression (proportion) of gephyrin
3) Confidence 0.15 Published 1998 Journal J. Cell. Sci. Section Abstract Doc Link 9427682 Disease Relevance 0 Pain Relevance 0.07
modulation of gephyrin and GABAA receptor expression
Regulation (modulation) of Gene_expression (expression) of gephyrin
4) Confidence 0.10 Published 2007 Journal Neural Plasticity Section Body Doc Link PMC1838961 Disease Relevance 0.18 Pain Relevance 0.51
Neural influence on protein kinase C isoform expression in skeletal muscle.
Regulation (influence) of Gene_expression (expression) of isoform in skeletal muscle associated with kinase c
5) Confidence 0.01 Published 1996 Journal J. Neurosci. Section Title Doc Link 8756430 Disease Relevance 0.05 Pain Relevance 0.48

General Comments

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