INT63869

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 3.84
Pain Relevance 2.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL1RAP) extracellular region (IL1RAP) plasma membrane (IL1RAP)
intracellular (IL1RAP) protein complex assembly (IL1RAP) signal transducer activity (IL1RAP)
Anatomy Link Frequency
leukocyte 2
plasma 1
IL1RAP (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 28 100.00 Very High Very High Very High
Angina 6 99.72 Very High Very High Very High
cytokine 36 95.12 Very High Very High Very High
Opioid 68 88.88 High High
Pain 34 78.24 Quite High
Inflammation 97 76.76 Quite High
analgesia 21 73.32 Quite High
epidural 2 72.92 Quite High
agonist 15 68.16 Quite High
IPN 19 60.12 Quite High
Disease Link Frequency Relevance Heat
Stable Angina Pectoris 6 99.72 Very High Very High Very High
Acute Coronary Syndrome 6 98.94 Very High Very High Very High
Necrosis 8 97.64 Very High Very High Very High
Cancer 7 97.46 Very High Very High Very High
Recurrence 2 90.04 High High
Disease 59 88.16 High High
Fistula 4 83.16 Quite High
Coronary Artery Disease 8 80.80 Quite High
Pain 35 78.24 Quite High
INFLAMMATION 105 76.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, the fold induction of the co-receptor IL-1RAcP was significantly reduced (1.00±0.03 for unstimulated (n?
Positive_regulation (induction) of IL-1RAcP
1) Confidence 0.45 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2914748 Disease Relevance 0 Pain Relevance 0
Interleukin-1 beta was increased by heparin (p < 0.05), whereas interleukin-1 receptor antagonist was increased by fentanyl (p < 0.05).
Positive_regulation (increased) of interleukin-1 receptor associated with antagonist
2) Confidence 0.06 Published 1996 Journal Anaesthesia Section Abstract Doc Link 8758154 Disease Relevance 0.71 Pain Relevance 0.36
Tumour necrosis factor-alpha and the interleukin-1 receptor antagonist were detectable in all children, and a trend towards an early increase in the interleukin-1 receptor antagonist levels at the end of surgery was seen.
Positive_regulation (increase) of interleukin-1 receptor associated with necrosis, cancer and antagonist
3) Confidence 0.06 Published 1998 Journal Eur J Anaesthesiol Section Abstract Doc Link 9522142 Disease Relevance 0.36 Pain Relevance 0.49
In contrast, TLR activation induces coupling to an adapter protein, MyD88, and stimulation of several intrinsic kinases including interleukin-1 receptor accessory protein kinase leading to NF-?
Positive_regulation (stimulation) of interleukin-1 receptor
4) Confidence 0.06 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2657213 Disease Relevance 0.24 Pain Relevance 0.61
At timed intervals amniotic fluid was sampled for leukocyte counts and assayed for prostaglandin E(2) and F(2alpha), the inflammatory cytokines interleukin 1beta, interleukin 6, interleukin 8, tumor necrosis factor alpha, and interleukin 1 receptor antagonist by specific assays.
Positive_regulation (assayed) of interleukin 1 receptor in leukocyte
5) Confidence 0.05 Published 2000 Journal Am. J. Obstet. Gynecol. Section Body Doc Link 10920327 Disease Relevance 0.06 Pain Relevance 0
Patients who had acute coronary syndrome and stable angina pectoris had significantly higher levels of C-reactive protein, interleukin-6, and interleukin-1 receptor antagonist than did controls, whereas levels of interleukin-2 receptor, interleukin-10, and interleukin-18 were similar across groups.
Positive_regulation (levels) of interleukin-1 receptor associated with stable angina pectoris, acute coronary syndrome, angina and antagonist
6) Confidence 0.02 Published 2005 Journal Am. J. Cardiol. Section Abstract Doc Link 15695127 Disease Relevance 0.88 Pain Relevance 0.53
Neutrophil counts, IL-1 receptor antagonist and soluble TNF receptors p55 and p75 plasma levels were increased during drug administration.
Positive_regulation (increased) of IL-1 receptor in plasma associated with antagonist
7) Confidence 0.01 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2621411 Disease Relevance 0.82 Pain Relevance 0.13
High levels of C-reactive protein, interleukin-6, and interleukin-1 receptor antagonist in patients were significantly related to numbers of neutrophils and neutrophil-platelet aggregates but not to other immune cell subpopulations.
Positive_regulation (levels) of interleukin-1 receptor in immune cell associated with antagonist
8) Confidence 0.01 Published 2005 Journal Am. J. Cardiol. Section Abstract Doc Link 15695127 Disease Relevance 0.76 Pain Relevance 0.50

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox