INT63901

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Context Info
Confidence 0.49
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.30
Pain Relevance 1.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Htr4) plasma membrane (Htr4) cytoplasm (Htr4)
signal transducer activity (Htr4)
Htr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 52 100.00 Very High Very High Very High
calcitonin gene related peptide 16 99.04 Very High Very High Very High
antagonist 23 96.12 Very High Very High Very High
qutenza 3 88.08 High High
tetrodotoxin 3 86.16 High High
dorsal root ganglion 2 79.92 Quite High
substance P 4 70.16 Quite High
Neurotransmitter 10 34.88 Quite Low
nud 14 9.60 Low Low
Pain 28 7.76 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 79.92 Quite High
Vibrio Infection 2 75.88 Quite High
Vomiting 6 10.24 Low Low
Dyspepsia 14 9.60 Low Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

122 5.00 Very Low Very Low Very Low
Constipation 54 5.00 Very Low Very Low Very Low
Diarrhoea 48 5.00 Very Low Very Low Very Low
Functional Bowel Disorder 26 5.00 Very Low Very Low Very Low
Pain 26 5.00 Very Low Very Low Very Low
Colitis 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stimulation of 5HT4 receptors by serotonin augments the release of Ach and CGRP.
Positive_regulation (augments) of Positive_regulation (Stimulation) of 5HT4 associated with calcitonin gene related peptide and serotonin
1) Confidence 0.49 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2503665 Disease Relevance 0.08 Pain Relevance 0.71
Stimulation of 5HT4 receptors on submucosal IPANs by serotonin augments the release of Ach and CGRP.
Positive_regulation (augments) of Positive_regulation (Stimulation) of 5HT4 associated with calcitonin gene related peptide and serotonin
2) Confidence 0.49 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2503665 Disease Relevance 0.07 Pain Relevance 0.67
These findings suggest that choleraic mucin secretion is mediated primarily through the activation of a 5-HT4-like receptor.
Positive_regulation (mediated) of Positive_regulation (activation) of 5-HT4-like
3) Confidence 0.29 Published 1996 Journal Am. J. Physiol. Section Abstract Doc Link 8764208 Disease Relevance 0.15 Pain Relevance 0.55

General Comments

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