INT63940

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Context Info
Confidence 0.13
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Vta1, Th) cytosol (Th) mitochondrion (Th)
nucleus (Th) response to stress (Th)
Anatomy Link Frequency
brain 2
Vta1 (Rattus norvegicus)
Th (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Ventral tegmentum 10 100.00 Very High Very High Very High
Morphine 9 100.00 Very High Very High Very High
cocaine 5 100.00 Very High Very High Very High
Dopamine 1 75.00 Quite High
Glutamate receptor 1 25.00 Low Low
Glutamate 1 25.00 Low Low
antagonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Toxicity 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Local infusion of brain-derived neurotrophic factor (BDNF) into the ventral tegmental area (VTA) can prevent and reverse the ability of chronic morphine or cocaine exposure to induce tyrosine hydroxylase (TH) in this brain region.
Negative_regulation (prevent) of VTA Positive_regulation (induce) of TH in brain associated with ventral tegmentum, cocaine and morphine
1) Confidence 0.13 Published 1996 Journal J. Neurosci. Section Abstract Doc Link 8764658 Disease Relevance 0 Pain Relevance 0.81

General Comments

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