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Context Info
Confidence 0.45
First Reported 1996
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 5.36
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein binding, bridging (Tnnt2) cytoplasm (Tnnt2)
Anatomy Link Frequency
muscle 1
skeletal muscle 1
Tnnt2 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 15 99.64 Very High Very High Very High
imagery 39 67.84 Quite High
ischemia 4 40.96 Quite Low
cytokine 1 21.36 Low Low
anesthesia 2 10.00 Low Low
GABAergic 10 5.00 Very Low Very Low Very Low
gABA 9 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Calcium channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Frailty 22 100.00 Very High Very High Very High
Cv General 3 Under Development 14 99.64 Very High Very High Very High
Myocardial Infarction 74 99.28 Very High Very High Very High
Chronic Renal Failure 28 98.36 Very High Very High Very High
Disease 71 97.36 Very High Very High Very High
Dermatomyositis 1 92.88 High High
Diabetes Mellitus 17 92.56 High High
Hyperlipidemia 22 92.20 High High
Targeted Disruption 22 90.60 High High
Congenital Anomalies 7 86.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSION: We conclude that elevated TnT levels in the postoperative period confer a 15-fold increase in mortality during the first year after surgery.
Regulation (confer) of TnT
1) Confidence 0.45 Published 2004 Journal Acta Anaesthesiol Scand Section Body Doc Link 15352951 Disease Relevance 0 Pain Relevance 0
One of the 38 patients with stable angina had an increased TnT value and died 5 months later of a noncardiac cause.
Regulation (value) of TnT associated with angina
2) Confidence 0.26 Published 1998 Journal Am. Heart J. Section Abstract Doc Link 9489973 Disease Relevance 0.83 Pain Relevance 0.37
Furthermore, MBNL1 has been shown to bind directly to intronic elements of genes misregulated in DM cardiac and skeletal muscle (cTNT and IR) and to promote alternative splicing patterns normally found in adult tissue [21].
Regulation (misregulated) of cTNT in skeletal muscle associated with frailty
3) Confidence 0.19 Published 2009 Journal PLoS Genetics Section Body Doc Link PMC2719092 Disease Relevance 1.07 Pain Relevance 0
RESULTS: In all cases with acute damage of the skeletal muscles (post operationem) the concentrations of TnT and TnI were in normal ranges. - In patients with chronic muscle diseases (M.
Regulation (concentrations) of TnT in muscle associated with disease
4) Confidence 0.13 Published 1996 Journal Med. Klin. (Munich) Section Abstract Doc Link 8767305 Disease Relevance 0.85 Pain Relevance 0.24
However, there are few studies describing the significance and the prognostic value of elevated serum cTnT levels in stable patients with moderate CKD [70].
Regulation (value) of cTnT associated with chronic renal failure
5) Confidence 0.06 Published 2011 Journal International Journal of Nephrology Section Body Doc Link PMC3017903 Disease Relevance 0.84 Pain Relevance 0.09
METHODS: Baseline TnT and CRP values were determined in 447 patients with unstable angina enrolled in the placebo group of the Chimeric c7E3 AntiPlatelet Therapy in Unstable angina REfractory to standard treatment trial (CAPTURE) trial.
Regulation (values) of TnT
6) Confidence 0.03 Published 2000 Journal J. Am. Coll. Cardiol. Section Body Doc Link 10807457 Disease Relevance 0.09 Pain Relevance 0
Serum TnT values in patients with AMI showed positive correlations with NT-proBNP (r = 0.28, p<0.01), CK-MB (r = 0.31, p<0.01) and MDA (r = 0.23, p<0.01) (Table 3).
Regulation (values) of TnT associated with myocardial infarction
7) Confidence 0.02 Published 2007 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2274989 Disease Relevance 1.68 Pain Relevance 0

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