INT63959

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Context Info
Confidence 0.21
First Reported 1996
Last Reported 2009
Negated 1
Speculated 1
Reported most in Abstract
Documents 11
Total Number 12
Disease Relevance 4.69
Pain Relevance 1.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tnni3)
Anatomy Link Frequency
chest 2
muscle 1
thoracic 1
Tnni3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cocaine 18 99.90 Very High Very High Very High
Angina 15 99.48 Very High Very High Very High
ischemia 5 97.96 Very High Very High Very High
Pain 3 97.32 Very High Very High Very High
imagery 3 5.00 Very Low Very Low Very Low
beta blocker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Natriuresis 1 100.00 Very High Very High Very High
Myocardial Infarction 44 99.80 Very High Very High Very High
Cv General 3 Under Development 8 99.48 Very High Very High Very High
Stress 9 99.20 Very High Very High Very High
Infarction 8 99.08 Very High Very High Very High
Coronary Artery Disease 9 98.40 Very High Very High Very High
Disease 6 97.68 Very High Very High Very High
Pain 3 97.32 Very High Very High Very High
Emergencies 3 97.16 Very High Very High Very High
Angina 7 96.16 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OBJECTIVE: The purpose of this study was to evaluate the in-hospital and follow-up prognostic value of cardiac troponin I in patients admitted in the Coronary Care Unit and discharged with the diagnosis of unstable angina.
Regulation (value) of cardiac troponin I associated with angina
1) Confidence 0.21 Published 1999 Journal Rev Port Cardiol Section Abstract Doc Link 10608161 Disease Relevance 0.17 Pain Relevance 0.17
RESULTS: In all cases with acute damage of the skeletal muscles (post operationem) the concentrations of TnT and TnI were in normal ranges. - In patients with chronic muscle diseases (M.
Regulation (concentrations) of TnI in muscle associated with disease
2) Confidence 0.19 Published 1996 Journal Med. Klin. (Munich) Section Abstract Doc Link 8767305 Disease Relevance 0.85 Pain Relevance 0.24
We studied the prognostic value of cardiac troponin I levels in patients with unstable angina or non-Q-wave myocardial infarction.
Regulation (value) of cardiac troponin I associated with angina and myocardial infarction
3) Confidence 0.11 Published 1996 Journal N. Engl. J. Med. Section Abstract Doc Link 8857017 Disease Relevance 0.36 Pain Relevance 0.10
To evaluate the sensitivity of the serum cardiac troponin I level in detecting stress test-induced myocardial ischemia, the authors conducted a prospective study including patients admitted for chest pain to the telemetry floor of Our Lady of Mercy Medical Center at Bronx, NY.
Regulation (sensitivity) of cardiac troponin I in chest associated with stress, angina, coronary artery disease and ischemia
4) Confidence 0.11 Published 2002 Journal Heart Dis Section Abstract Doc Link 12147181 Disease Relevance 0.69 Pain Relevance 0.18
OBJECTIVE: We measured the diagnostic value of troponin I (TnI), mioglobin (Miog) and creatine kinase MB (CPK-MB) in patients with thoracic pain during the period of preadmission to the hospital.
Regulation (value) of TnI in thoracic associated with pain
5) Confidence 0.08 Published 2006 Journal Cir Cir Section Abstract Doc Link 17022893 Disease Relevance 0.25 Pain Relevance 0.10
Sensitivity of TnI, Miog, and CPK-MB was 100%, specificity was 94, 91 and 94%, respectively.
Regulation (Sensitivity) of TnI
6) Confidence 0.08 Published 2006 Journal Cir Cir Section Body Doc Link 17022893 Disease Relevance 0.06 Pain Relevance 0
The specificity of CK-MB was affected less and the specificity of cardiac troponin I was not affected by recent cocaine use.
Neg (not) Regulation (affected) of cardiac troponin I associated with cocaine
7) Confidence 0.05 Published 1998 Journal Am. Heart J. Section Abstract Doc Link 9489972 Disease Relevance 0.54 Pain Relevance 0.39
The 100% negative predictive value is particularly important because it indicates that patients with negative CK-MB and cardiac troponin I values 12 hours after admission have a negligible likelihood of AMI.


Regulation (values) of cardiac troponin I
8) Confidence 0.05 Published 1998 Journal Arch. Pathol. Lab. Med. Section Body Doc Link 9648898 Disease Relevance 0 Pain Relevance 0
Among various laboratory data, the peak levels of creatine kinase MB (CK-MB), TnI, and N-terminal pro b-type natriuretic peptide (NT-pro-BNP) were evaluated for estimation of the infarction burden.
Regulation (evaluated) of TnI associated with natriuresis and infarction
9) Confidence 0.04 Published 2009 Journal Korean Circulation Journal Section Body Doc Link PMC2771835 Disease Relevance 1.02 Pain Relevance 0.07
HYPOTHESIS: A multicenter study was conducted to evaluate the efficacy of cardiac troponin I (cTnI) in detecting and ruling out AMI.
Regulation (efficacy) of cardiac troponin I
10) Confidence 0.02 Published 1997 Journal Clin Cardiol Section Body Doc Link 9068915 Disease Relevance 0.09 Pain Relevance 0
CONCLUSION: The diagnostic accuracy in detecting myocardial damage early in the Emergency Cardiology Department improves when the 99th percentile is used as a decisional value of cardiac troponin I; the use of this cut-off makes the measurement of myoglobin unnecessary.


Regulation (value) of cardiac troponin I
11) Confidence 0.02 Published 2007 Journal Coron. Artery Dis. Section Body Doc Link 17429291 Disease Relevance 0 Pain Relevance 0
We evaluated whether recent cocaine use alters the specificity of CK-MB, myoglobin, and cardiac troponin I for acute myocardial infarction (AMI) in patients who are seen in the emergency department for chest pain.
Spec (whether) Regulation (alters) of cardiac troponin I in chest associated with angina, emergencies, myocardial infarction and cocaine
12) Confidence 0.01 Published 1998 Journal Am. Heart J. Section Abstract Doc Link 9489972 Disease Relevance 0.66 Pain Relevance 0.32

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