INT6407

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Context Info
Confidence 0.02
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) extracellular space (Lama5) extracellular region (Lama5)
cell adhesion (Lama5) proteinaceous extracellular matrix (Lama5) plasma membrane (Oprm1)
Lama5 (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 5 98.20 Very High Very High Very High
analgesia 7 93.08 High High
Morphine 3 90.64 High High
Opioid 1 90.00 High High
intrathecal 1 83.96 Quite High
Analgesic 4 81.16 Quite High
Central grey 1 78.00 Quite High
opioid receptor 4 75.00 Quite High
agonist 2 75.00 Quite High
Potency 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1 78.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In binding studies TRIMU-5 had high affinity for mu 1 sites, but pharmacological studies revealed antagonist actions at this receptor.
TRIMU-5 Binding (affinity) of mu 1 associated with antagonist
1) Confidence 0.02 Published 1992 Journal Eur. J. Pharmacol. Section Abstract Doc Link 1327812 Disease Relevance 0.08 Pain Relevance 1.72

General Comments

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