INT64075

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Context Info
Confidence 0.02
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.55
Pain Relevance 1.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Kcnma1) plasma membrane (Kcnma1)
Kcnma1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 99 99.84 Very High Very High Very High
antagonist 2 92.56 High High
dorsal root ganglion 5 91.76 High High
Root ganglion neuron 1 75.00 Quite High
Pain 63 74.08 Quite High
burning pain 1 72.72 Quite High
nociceptor 44 66.48 Quite High
Inflammation 17 50.00 Quite Low
Hyperalgesia 18 46.12 Quite Low
central sensitization 2 44.08 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 91.76 High High
Pain 59 74.08 Quite High
Inflammatory Pain 6 50.00 Quite Low
Hyperalgesia 43 46.12 Quite Low
INFLAMMATION 17 28.68 Quite Low
Injury 4 27.20 Quite Low
Nociception 14 24.24 Low Low
Heart Rate Under Development 3 5.00 Very Low Very Low Very Low
Cold Sores 3 5.00 Very Low Very Low Very Low
Herpes Simplex Virus 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In solution containing 140 mM Na+, extracellular application of CAP to outside-out patches caused activation of an ion channel in a concentration-dependent manner (EC50 = 1.1 microM).
Positive_regulation (caused) of Positive_regulation (activation) of channel associated with qutenza
1) Confidence 0.02 Published 1996 Journal J. Neurosci. Section Abstract Doc Link 8774434 Disease Relevance 0.34 Pain Relevance 0.91
The capsaicin insensitivity of the avian TRPV1 was used to determine the amino acid residues that are required for channel activation by capsaicin [10].
Positive_regulation (required) of Positive_regulation (activation) of channel associated with qutenza
2) Confidence 0.01 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2214810 Disease Relevance 0.21 Pain Relevance 1.05

General Comments

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