INT64123

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.70
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 16
Total Number 16
Disease Relevance 5.77
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PIP) biological_process (PIP)
Anatomy Link Frequency
lymph nodes 1
lungs 1
PIP (Homo sapiens)
Pain Link Frequency Relevance Heat
noradrenaline 1 98.62 Very High Very High Very High
Dopamine 1 98.26 Very High Very High Very High
abdominal pain 1 93.20 High High
cytokine 2 82.44 Quite High
fibrosis 3 80.24 Quite High
Neurotransmitter 1 78.72 Quite High
imagery 5 77.72 Quite High
potassium channel 2 76.28 Quite High
sodium channel 2 74.52 Quite High
qutenza 1 65.88 Quite High
Disease Link Frequency Relevance Heat
Advanced Or Metastatic Breast Cancer 21 99.84 Very High Very High Very High
Metastasis 64 99.68 Very High Very High Very High
Breast Cancer 210 99.30 Very High Very High Very High
Cancer 414 98.00 Very High Very High Very High
Abdominal Pain 1 93.20 High High
Adrenal Insufficiency 2 91.76 High High
Adrenal Cancer 5 81.00 Quite High
Cystic Fibrosis 1 80.24 Quite High
Cv General 4 Under Development 3 79.92 Quite High
Pressure And Volume Under Development 1 76.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Comparison of the results using gene-panel data did not show statistically significant association, however, the results of mam and PIP gene expression in PBL had statistically significant association with the mam and PIP gene expression in BM (p = 2.5E-04 and p = 0.0188, respectively).


Gene_expression (expression) of PIP
1) Confidence 0.70 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.06 Pain Relevance 0
Comparison of the results using gene-panel data did not show statistically significant association, however, the results of mam and PIP gene expression in PBL had statistically significant association with the mam and PIP gene expression in BM (p = 2.5E-04 and p = 0.0188, respectively).


Gene_expression (expression) of PIP
2) Confidence 0.70 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.06 Pain Relevance 0
In our study, marker positivity in BM had no statistically significant association with any of the traditional prognostic indicators, however, the results of mam and PIP gene expression in PBL had statistically significant association with the mam and PIP gene expression in BM (p = 2.5E-04 and p = 0.0188, respectively; Table 4).
Gene_expression (expression) of PIP
3) Confidence 0.70 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.38 Pain Relevance 0
In our study, marker positivity in BM had no statistically significant association with any of the traditional prognostic indicators, however, the results of mam and PIP gene expression in PBL had statistically significant association with the mam and PIP gene expression in BM (p = 2.5E-04 and p = 0.0188, respectively; Table 4).
Gene_expression (expression) of PIP
4) Confidence 0.70 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.32 Pain Relevance 0
We suggest that this result shows the close connection of PBL and BM compartments and that mam and PIP overexpression is not random but truly indicate the presence of tumor cells.
Gene_expression (overexpression) of PIP associated with cancer
5) Confidence 0.70 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.32 Pain Relevance 0
Although administration of dopamine and noradrenaline was started and the inhaled concentration of NO was increased, sPAP overwhelmed sABP after all.
Gene_expression (overwhelmed) of sABP associated with dopamine and noradrenaline
6) Confidence 0.66 Published 2010 Journal Masui Section Abstract Doc Link 20169963 Disease Relevance 0.42 Pain Relevance 0.10
Such domains may serve to localize PIP(2) and thereby PIP(2) signaling, as well as to organize PIP(2) binding partners into signaling complexes.
Gene_expression (organize) of PIP
7) Confidence 0.65 Published 2001 Journal Sci. STKE Section Abstract Doc Link 11734659 Disease Relevance 0.08 Pain Relevance 0.27
Using the five-marker gene-panel (mam, PIP, CEA, PSE and EpCAM) at the threshold of three standard deviations above the mean expression level in normal control samples for each gene, 136 (63%) patients out of 215 were positive for at least one marker.
Gene_expression (expression) of PIP
8) Confidence 0.61 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.47 Pain Relevance 0
Using a four-marker gene-panel (mam, PIP, CEA, and PSE) at the threshold of three standard deviations above the mean expression level in normal control samples for each gene, 19 patients (11%) out of 177 were positive.
Gene_expression (expression) of PIP
9) Confidence 0.61 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.26 Pain Relevance 0
For this study we selected seven breast cancer-associated genes [mam, CEA, CK19, PIP, muc1, PSE, Erb (BM only) and EpCAM (PBL only)] known to be over-expressed in metastatic breast cancer compared to control lymph nodes [31,36,37].
Gene_expression (expressed) of PIP in lymph nodes associated with breast cancer and advanced or metastatic breast cancer
10) Confidence 0.55 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.66 Pain Relevance 0
Takeda Y [14] reported that of 20 cases of metastatic breast carcinoma reaching the lungs, 10 (50.0%) were immunoreactive for mammaglobin and 9 (45.0%) for GCDFP-15 in the metastatic tumors.
Gene_expression (immunoreactive) of GCDFP-15 in lungs associated with breast cancer and metastasis
11) Confidence 0.54 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2824745 Disease Relevance 1.96 Pain Relevance 0.22
Two out of these five samples were also positive by RT-PCR (one for mam and another for PIP).
Gene_expression (one) of PIP
12) Confidence 0.53 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2292197 Disease Relevance 0.45 Pain Relevance 0
To address these questions, we dialyzed rats for 3 h in the supine position at constant levels of Pip with isotonic and hypertonic dialysis solutions containing a protein marker of fluid movement.
Gene_expression (levels) of Pip
13) Confidence 0.53 Published 1996 Journal Am. J. Physiol. Section Abstract Doc Link 8779900 Disease Relevance 0.08 Pain Relevance 0
FOY-007 attenuated the collagen synthesis and PIP production stimulated by TGF-beta1 dose dependently, but FOY-305 inhibited only PIP production.
Gene_expression (production) of PIP
14) Confidence 0.27 Published 2001 Journal Pancreas Section Abstract Doc Link 11291936 Disease Relevance 0.12 Pain Relevance 0.13
FOY-007 attenuated the collagen synthesis and PIP production stimulated by TGF-beta1 dose dependently, but FOY-305 inhibited only PIP production.
Gene_expression (production) of PIP
15) Confidence 0.27 Published 2001 Journal Pancreas Section Abstract Doc Link 11291936 Disease Relevance 0.13 Pain Relevance 0.14
Membrane lipid and PIP arrays
Gene_expression (arrays) of PIP
16) Confidence 0.03 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2909203 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox