INT64172

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.19
First Reported 1996
Last Reported 1996
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CPOX) small molecule metabolic process (CPOX) oxidoreductase activity (CPOX)
cytoplasm (CPOX)
Anatomy Link Frequency
macrophages 4
CPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 8 100.00 Very High Very High Very High
aspirin 4 89.92 High High
COX2 2 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 92.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrate that NSAID's action in human macrophages is not directed towards the transcription or translation of the COX genes but only to the enzymatic activity of the proteins.
Neg (not) Regulation (directed) of Transcription (transcription) of COX in macrophages associated with cinod
1) Confidence 0.19 Published 1996 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 8780708 Disease Relevance 0.14 Pain Relevance 0.36
In this study we evaluated the effect of several NSAIDs on COX-1 and COX-2 mRNA, protein expression and PGE2 production in PMA-differentiated THP-1 and U937 human macrophages stimulated with LPS.
Regulation (effect) of Transcription (expression) of COX in macrophages associated with cinod
2) Confidence 0.11 Published 1996 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 8780708 Disease Relevance 0.17 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox