INT64259

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Context Info
Confidence 0.06
First Reported 1996
Last Reported 1996
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ptprg) Golgi apparatus (Gtpbp4) nucleolus (Gtpbp4)
nucleus (Gtpbp4) GTPase activity (Gtpbp4) ribosome biogenesis (Gtpbp4)
Anatomy Link Frequency
brain 1
Gtpbp4 (Rattus norvegicus)
Ptprg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 7 100.00 Very High Very High Very High
MU agonist 1 100.00 Very High Very High Very High
mu opioid receptor 3 99.82 Very High Very High Very High
addiction 1 94.04 High High
tolerance 2 93.44 High High
opiate 2 91.24 High High
Opioid 3 81.20 Quite High
agonist 2 69.52 Quite High
Raphe 1 40.00 Quite Low
Locus ceruleus 1 38.80 Quite Low
Disease Link Frequency Relevance Heat
Drug Dependence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To localize changes in mu opioid receptor-coupled G-protein activity in various brain regions after chronic morphine treatment, the present study examined mu opioid agonist-stimulated [35S]GTPgammaS binding to brain sections by in vitro autoradiography.
G-protein Spec (examined) Binding (binding) of GTPgammaS in brain associated with mu agonist, mu opioid receptor and morphine
1) Confidence 0.06 Published 1996 Journal J. Neurosci. Section Abstract Doc Link 8786444 Disease Relevance 0 Pain Relevance 1.10

General Comments

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