INT64648

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Context Info
Confidence 0.23
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 4
Total Number 4
Disease Relevance 1.63
Pain Relevance 2.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Selenbp2) nucleus (Selenbp2) cytoplasm (Selenbp2)
Selenbp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 46 100.00 Very High Very High Very High
Analgesic 3 97.88 Very High Very High Very High
Versed 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 7 98.98 Very High Very High Very High
Targeted Disruption 22 97.48 Very High Very High Very High
Nephrotoxicity 4 96.40 Very High Very High Very High
Hepatotoxicity 2 96.32 Very High Very High Very High
Overdose 2 94.12 High High
Diabetes Mellitus 1 74.36 Quite High
Alzheimer's Dementia 4 71.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Selenium-binding protein 2, the major hepatic target for acetaminophen, shows sex differences in protein abundance.
Regulation (target) of Selenium-binding protein 2 associated with paracetamol
1) Confidence 0.23 Published 2006 Journal Electrophoresis Section Title Doc Link 16532517 Disease Relevance 0 Pain Relevance 0.29
Associated with target organ toxicity is selective arylation of proteins, with a 58-kDa acetaminophen binding protein (58-ABP) being the most prominent cytosolic target.
Regulation (target) of acetaminophen binding protein associated with toxicity and paracetamol
2) Confidence 0.17 Published 1996 Journal Fundam Appl Toxicol Section Abstract Doc Link 8937897 Disease Relevance 0.74 Pain Relevance 0.82
Evidence suggesting the 58-kDa acetaminophen binding protein is a preferential target for acetaminophen electrophile.
Regulation (target) of acetaminophen binding protein associated with paracetamol
3) Confidence 0.14 Published 1996 Journal Fundam Appl Toxicol Section Title Doc Link 8812234 Disease Relevance 0.28 Pain Relevance 0.84
acetaminophen-test [17], to control for any differences in gastric emptying between
Regulation (control) of acetaminophen-test associated with paracetamol
4) Confidence 0.00 Published 2008 Journal Experimental Diabetes Research Section Body Doc Link PMC2443691 Disease Relevance 0.61 Pain Relevance 0.10

General Comments

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