INT64709

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Context Info
Confidence 0.67
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 12
Disease Relevance 11.01
Pain Relevance 1.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VTN) extracellular region (VTN) cell adhesion (VTN)
proteinaceous extracellular matrix (VTN) extracellular matrix organization (VTN)
Anatomy Link Frequency
spike 2
platelets 1
VTN (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 151 98.80 Very High Very High Very High
cva 85 97.28 Very High Very High Very High
abdominal pain 2 97.00 Very High Very High Very High
Osteoarthritis 56 94.16 High High
Angina 2 93.56 High High
antagonist 17 91.44 High High
Inflammation 19 89.52 High High
imagery 9 86.20 High High
fibrosis 8 74.80 Quite High
Migraine 4 66.04 Quite High
Disease Link Frequency Relevance Heat
Thrombosis Related Under Development 62 99.90 Very High Very High Very High
Severe Acute Respiratory Syndrome 358 99.80 Very High Very High Very High
Adhesions 173 99.76 Very High Very High Very High
Coagulation Disorder 9 99.52 Very High Very High Very High
Rheumatoid Arthritis 151 98.80 Very High Very High Very High
Shock 5 97.40 Very High Very High Very High
Abdominal Pain 2 97.00 Very High Very High Very High
Systemic Lupus Erythematosus 5 95.40 Very High Very High Very High
Thrombophilia 161 94.80 High High
Osteoarthritis 56 94.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[Atypical venous thrombosis and protein S deficiency: report of a case].
Gene_expression (deficiency) of protein S associated with thrombosis related under development
1) Confidence 0.67 Published 2005 Journal Ann Cardiol Angeiol (Paris) Section Title Doc Link 16104624 Disease Relevance 0.74 Pain Relevance 0.22
Accurate hematological screening before reoperation showed decreased levels of protein S.
Gene_expression (levels) of protein S
2) Confidence 0.52 Published 1996 Journal Eur J Cardiothorac Surg Section Abstract Doc Link 8817147 Disease Relevance 0.44 Pain Relevance 0.09
Protein C and Protein S deficiencies are genetic traits predisposing to the formation of venous clots.
Gene_expression (deficiencies) of Protein S
3) Confidence 0.38 Published 2004 Journal Thromb J Section Body Doc Link PMC415559 Disease Relevance 0.72 Pain Relevance 0.12
For these reasons, we selected fibronectin, vitronectin, and Coll.I for our study of RA-FLS adhesion.
Gene_expression (selected) of vitronectin associated with rheumatoid arthritis and adhesions
4) Confidence 0.34 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991025 Disease Relevance 1.54 Pain Relevance 0.63
RA-FLSs exposed to adrenomedullin exhibited a spread-out shape on vitronectin after 2 hours, whereas the cells remained round on BSA (Figure 1c); no cell-to-cell adhesion was observed at higher-power field (not shown).
Gene_expression (round) of vitronectin associated with rheumatoid arthritis and adhesions
5) Confidence 0.29 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991025 Disease Relevance 1.25 Pain Relevance 0.26
Meanwhile, the following tests were ordered to rule out a coagulopathy: protein C deficiency, protein S deficiency, factor V Leiden, factor II 20210, anti-cardiolipin antibody studies, anti-thrombin III, factor II and fibrinogen levels, and all were all within the normal limits.
Gene_expression (deficiency) of protein S associated with coagulation disorder
6) Confidence 0.06 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2868875 Disease Relevance 0.70 Pain Relevance 0.18
The granules also contain vitronectin, a cell adhesion molecule which helps with osseointegration and osseoconduction.Fig. 1Inactive platelets
Gene_expression (contain) of vitronectin in platelets associated with adhesions
7) Confidence 0.05 Published 2008 Journal Curr Rev Musculoskelet Med Section Body Doc Link PMC2682411 Disease Relevance 0.26 Pain Relevance 0.08
Additional risk factors, such as AT III deficiency or protein C and protein S deficiencies were present in 25 percent of women with a history of VTE, as compared with 11 percent of women with no history.
Gene_expression (deficiency) of protein S associated with cva
8) Confidence 0.01 Published 2003 Journal Reprod Biol Endocrinol Section Body Doc Link PMC305329 Disease Relevance 0.66 Pain Relevance 0.23
Eight recombinant human single-chain variable region fragments (scFvs) against the S1 domain of spike (S) protein of the SARS-CoV from two nonimmune human antibody libraries were screened and one scFv 80R efficiently neutralized SARS-CoV and inhibited syncytia formation between cells expressing the S protein and those expressing the SARS-CoV receptor angiotensin-converting enzyme 2 (ACE2) [117].
Gene_expression (expressing) of S protein in spike associated with severe acute respiratory syndrome
9) Confidence 0.01 Published 2005 Journal Respir Res Section Body Doc Link PMC548145 Disease Relevance 1.22 Pain Relevance 0
Eight recombinant human single-chain variable region fragments (scFvs) against the S1 domain of spike (S) protein of the SARS-CoV from two nonimmune human antibody libraries were screened and one scFv 80R efficiently neutralized SARS-CoV and inhibited syncytia formation between cells expressing the S protein and those expressing the SARS-CoV receptor angiotensin-converting enzyme 2 (ACE2) [117].
Gene_expression (expressing) of S protein in spike associated with severe acute respiratory syndrome
10) Confidence 0.01 Published 2005 Journal Respir Res Section Body Doc Link PMC548145 Disease Relevance 1.23 Pain Relevance 0
2-glycoprotein I antibodies, factor II G20210A mutation, factor V Leiden mutation, anti-thrombin, protein C and protein S) showed low level of free protein S antigen (37% normal > 55%).
Gene_expression (mutation) of protein S
11) Confidence 0.01 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2836274 Disease Relevance 1.61 Pain Relevance 0.15
Surprisingly, we found several novel domains in the N-termini of the amphioxus Adhesion GPCRs like Somatomedin B, Kringle, Lectin C-type and SRCR (for more details see Fig. 2) which to our knowledge are unique for amphioxus among the GPCRs.
Gene_expression (see) of Somatomedin B associated with adhesions
12) Confidence 0.01 Published 2008 Journal BMC Evol Biol Section Body Doc Link PMC2246102 Disease Relevance 0.65 Pain Relevance 0

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