INT64883

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.03
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 7
Disease Relevance 1.26
Pain Relevance 3.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ina) structural molecule activity (Ina) plasma membrane (Ptger2)
signal transducer activity (Ptger2)
Anatomy Link Frequency
PGE2 7
Ptger2 (Rattus norvegicus)
Ina (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Root ganglion neuron 7 99.16 Very High Very High Very High
narcan 7 98.94 Very High Very High Very High
nociceptor 14 94.96 High High
tetrodotoxin 7 92.08 High High
Enkephalin 14 88.92 High High
MU agonist 7 87.40 High High
Hyperalgesia 7 73.36 Quite High
Opioid 7 61.36 Quite High
antinociception 7 60.16 Quite High
Analgesic 7 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 7 98.84 Very High Very High Very High
Hyperalgesia 21 81.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Preapplication of naloxone (10 microM) blocked DAMGO-induced inhibition of the PGE2-induced increase in TTX-R INa.
PGE2 Positive_regulation (increase) of TTX-R INa in PGE2 associated with narcan
1) Confidence 0.03 Published 1996 Journal Neurosci. Lett. Section Abstract Doc Link 8832644 Disease Relevance 0.23 Pain Relevance 0.65
In contrast, when DAMGO was applied after PGE2, PGE2-induced increase in TTX-R INa (85.3 +/- 19.6%) was not significantly different than the increase in the current induced by PGE2 alone.
PGE2 Positive_regulation (increase) of TTX-R INa in PGE2
2) Confidence 0.03 Published 1996 Journal Neurosci. Lett. Section Abstract Doc Link 8832644 Disease Relevance 0.21 Pain Relevance 0.53
The PGE2-induced increase in TTX-R INa in the presence of 1 microM DAMGO (24.9 +/- 7.7%), was significantly less than that induced by PGE2 alone.
PGE2 Positive_regulation (increase) of TTX-R INa in PGE2
3) Confidence 0.03 Published 1996 Journal Neurosci. Lett. Section Abstract Doc Link 8832644 Disease Relevance 0.10 Pain Relevance 0.44
PGE2 (1 microM) induced a 103 +/- 22.8% increase in peak TTX-R INa.
PGE2 Positive_regulation (increase) of TTX-R INa in PGE2
4) Confidence 0.03 Published 1996 Journal Neurosci. Lett. Section Abstract Doc Link 8832644 Disease Relevance 0.10 Pain Relevance 0.45
In contrast, when DAMGO was applied after PGE2, PGE2-induced increase in TTX-R INa (85.3 +/- 19.6%) was not significantly different than the increase in the current induced by PGE2 alone.
PGE2 Positive_regulation (increase) of TTX-R INa in PGE2
5) Confidence 0.01 Published 1996 Journal Neurosci. Lett. Section Abstract Doc Link 8832644 Disease Relevance 0.21 Pain Relevance 0.53
In contrast, when DAMGO was applied after PGE2, PGE2-induced increase in TTX-R INa (85.3 +/- 19.6%) was not significantly different than the increase in the current induced by PGE2 alone.
PGE2 Positive_regulation (increase) of TTX-R INa in PGE2
6) Confidence 0.01 Published 1996 Journal Neurosci. Lett. Section Abstract Doc Link 8832644 Disease Relevance 0.21 Pain Relevance 0.53
In contrast, when DAMGO was applied after PGE2, PGE2-induced increase in TTX-R INa (85.3 +/- 19.6%) was not significantly different than the increase in the current induced by PGE2 alone.
PGE2 Positive_regulation (increase) of TTX-R INa in PGE2
7) Confidence 0.00 Published 1996 Journal Neurosci. Lett. Section Abstract Doc Link 8832644 Disease Relevance 0.21 Pain Relevance 0.53

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox