INT64899

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Context Info
Confidence 0.33
First Reported 1995
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 2.82
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

molecular_function (NAAA) transcription factor binding (NAAA) biological_process (NAAA)
lipid metabolic process (NAAA) lysosome (NAAA) cytoplasm (NAAA)
Anatomy Link Frequency
smooth muscle 1
blood vessel 1
plaque 1
PLT 1
NAAA (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 4 99.48 Very High Very High Very High
Pain 3 98.44 Very High Very High Very High
Inflammatory response 1 98.20 Very High Very High Very High
Inflammation 62 97.80 Very High Very High Very High
Inflammatory mediators 10 88.52 High High
Angina 2 75.00 Quite High
anesthesia 1 48.76 Quite Low
rheumatoid arthritis 15 40.36 Quite Low
cINOD 22 5.00 Very Low Very Low Very Low
aspirin 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Coronary Heart Disease 4 99.88 Very High Very High Very High
Obesity 12 99.76 Very High Very High Very High
Pancreatitis 4 99.48 Very High Very High Very High
Pain 2 98.44 Very High Very High Very High
Fever 4 98.26 Very High Very High Very High
INFLAMMATION 84 98.20 Very High Very High Very High
Increased Venous Pressure Under Development 5 96.36 Very High Very High Very High
Acute Coronary Syndrome 5 93.64 High High
Disease 129 84.20 Quite High
Disorder Of Lipid Metabolism 23 77.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results suggest that with PLT, NBT-PABA and CH impaired pancreatic function may be succesfully recognized in advanced chronic pancreatitis, in particular, when two of them are applied concomittantly.
PLT Binding (recognized) of associated with chronic pancreatitis
1) Confidence 0.33 Published 1995 Journal Pol. Arch. Med. Wewn. Section Abstract Doc Link 8834125 Disease Relevance 0.29 Pain Relevance 0.29
Platelet (PLT)-endothelial cell and PLT-leukocyte interactions at lesion-prone sites might trigger a local inflammatory response early in the genesis of atherosclerosis and contribute to plaque destabilization leading to acute coronary syndromes (ACS).
PLT Binding (interactions) of in plaque associated with acute coronary syndrome, inflammatory response and increased venous pressure under development
2) Confidence 0.21 Published 2007 Journal Platelets Section Abstract Doc Link 17365849 Disease Relevance 0.78 Pain Relevance 0.18
So, we proposed that fibrinogen and PLT transfusion in combination should be better for infants with high HCT CCHD, but PLT alone might be enough for low HCT ones.
PLT Spec (might) Binding (enough) of in PLT associated with coronary heart disease
3) Confidence 0.12 Published 2009 Journal Artif Organs Section Abstract Doc Link 20021469 Disease Relevance 0.10 Pain Relevance 0
As the ratio of PMN, EC and PLT depends on the size of the blood vessel, we simulated the metabolism of AA in a 1-cm long and 50-?
PLT Binding (ratio) of in blood vessel
4) Confidence 0.09 Published 2008 Journal Mol Syst Biol Section Body Doc Link PMC2673713 Disease Relevance 0.22 Pain Relevance 0
PGE2 is an important inflammatory mediator causing fever and pain (Ivanov and Romanovsky, 2004; Samuelsson et al, 2007), whereas PGI2 inhibits PLT aggregation and relaxes smooth muscle (Honn et al, 1981).
PLT Binding (aggregation) of in smooth muscle associated with pain, inflammation and fever
5) Confidence 0.09 Published 2008 Journal Mol Syst Biol Section Body Doc Link PMC2673713 Disease Relevance 1.04 Pain Relevance 0.38
Table 3 shows the serum PGE2, FBS, CRP concentrations, AEA, ESR, WBC, PLT, and BMI before and after supplementation for subjects who completed the study.
PLT Binding (shows) of associated with obesity
6) Confidence 0.03 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2663461 Disease Relevance 0.39 Pain Relevance 0

General Comments

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