INT64929

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Context Info
Confidence 0.41
First Reported 1996
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.75
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (LEPRE1) endoplasmic reticulum (LEPRE1) proteinaceous extracellular matrix (LEPRE1)
nucleus (LEPRE1) molecular_function (LEPRE1) cellular_component (LEPRE1)
Anatomy Link Frequency
pancreas 1
LEPRE1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 7 98.64 Very High Very High Very High
metalloproteinase 5 94.88 High High
alcohol 4 84.80 Quite High
Pain 6 82.60 Quite High
Chronic pancreatitis 2 64.64 Quite High
Autonomic response 1 25.00 Low Low
medulla 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Fibrosis 7 98.64 Very High Very High Very High
Nociception 1 98.52 Very High Very High Very High
Hepatotoxicity 1 84.36 Quite High
Pancreatitis 2 64.64 Quite High
Pain 2 46.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conditioning by remote noxious stimulation (RNS; application of 3 degrees C water to a hand) usually produced increases in activity at the Q-R and S-T transitions of the PSEC (at mean latencies of 24 and 54 ms respectively), which resulted principally from a shortening of the inhibitory Q and S waves.
Positive_regulation (increases) of PSEC
1) Confidence 0.41 Published 1996 Journal Brain Res. Section Abstract Doc Link 8836560 Disease Relevance 0 Pain Relevance 0.08
Both MEx and RNS caused increases in EMG activity around the Q-R and S-T transitions of the PSEC, which resulted principally from shortenings of the inhibitory Q and S waves.
Positive_regulation (increases) of PSEC
2) Confidence 0.24 Published 2000 Journal Pain Section Abstract Doc Link 10666524 Disease Relevance 0.10 Pain Relevance 0.08
Prolyl hydroxylase in pancreas tissue is increased in the early stage of pancreatic fibrosis.
Positive_regulation (increased) of Prolyl hydroxylase in pancreas associated with fibrosis
3) Confidence 0.24 Published 2007 Journal Rinsho Byori Section Abstract Doc Link 17882797 Disease Relevance 0.65 Pain Relevance 0.62

General Comments

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