INT64935

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Context Info
Confidence 0.26
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Itpr3) endoplasmic reticulum (Itpr3) nucleolus (Itpr3)
nucleus (Itpr3) transmembrane transport (Itpr3) cytoplasm (Itpr3)
Anatomy Link Frequency
myocytes 2
Itpr3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kappa opioid receptor 8 100.00 Very High Very High Very High
opioid receptor 1 96.52 Very High Very High Very High
Dynorphin 1 91.36 High High
agonist 2 90.92 High High
tolerance 2 62.88 Quite High
Opioid 1 30.32 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The responses of IP3 and [Ca2+]i to kappa-opioid receptor stimulation were abolished in myocytes of rats that had received chronic injection of U50,488H for 4 days. kappa-Opioid receptor stimulation with U50,488H also reduced the [Ca2+]i transient, induced by electrical stimulation and caffeine, both known to mobilize [Ca2+]i.
Negative_regulation (abolished) of Regulation (responses) of IP3 in myocytes associated with kappa opioid receptor and opioid receptor
1) Confidence 0.26 Published 1996 Journal Eur. J. Pharmacol. Section Abstract Doc Link 8836621 Disease Relevance 0 Pain Relevance 0.49

General Comments

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