INT64959

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.42
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 5.16
Pain Relevance 1.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6) aging (IL6) extracellular region (IL6)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 42 100.00 Very High Very High Very High
Chronic pancreatitis 33 99.64 Very High Very High Very High
fibrosis 23 98.84 Very High Very High Very High
Inflammatory marker 4 98.72 Very High Very High Very High
Inflammation 53 94.80 High High
Pain 6 83.28 Quite High
cINOD 3 75.76 Quite High
chemokine 5 71.36 Quite High
rheumatoid arthritis 2 50.00 Quite Low
psoriasis 1 47.12 Quite Low
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 77 99.84 Very High Very High Very High
Cancer 68 99.80 Very High Very High Very High
Pancreatitis 33 99.64 Very High Very High Very High
Necrosis 5 99.56 Very High Very High Very High
Cystic Fibrosis 15 98.84 Very High Very High Very High
Stress 7 98.82 Very High Very High Very High
INFLAMMATION 60 98.40 Very High Very High Very High
Syndrome 25 98.40 Very High Very High Very High
Sepsis 15 96.48 Very High Very High Very High
Fatigue 6 96.08 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tenidap induced a somewhat similar reduction pattern of IL-1 beta and IL-6 mRNA to that observed for cytokine synthesis.
Positive_regulation (induced) of Negative_regulation (reduction) of IL-6
1) Confidence 0.42 Published 1996 Journal J. Rheumatol. Section Body Doc Link 8838503 Disease Relevance 0 Pain Relevance 0
CRP secretion is increased in response to a complex network of cytokines, especially IL-6 and either IL-1 or tumor necrosis factor (TNF-?)
Positive_regulation (response) of Negative_regulation (network) of IL-6 associated with necrosis, cancer and cytokine
2) Confidence 0.28 Published 2010 Journal International Journal of Inflammation Section Body Doc Link PMC2989710 Disease Relevance 1.31 Pain Relevance 0.22
Following coculture with donor and CP PBMC, expression levels of IL-6, MCP-1 and IL-8 were increased in PSC (Figure 6A; all p < 0.05).
Positive_regulation (increased) of Negative_regulation (levels) of IL-6 associated with primary sclerosing cholangitis and chronic pancreatitis
3) Confidence 0.15 Published 2007 Journal J Transl Med Section Body Doc Link PMC2234395 Disease Relevance 1.11 Pain Relevance 0.59
On the basis of these results, we started a phase III randomized clinical trial to establish which was the most effective and safest treatment of CACS and oxidative stress in improving selected key variables as primary endpoints: increase of LBM, decrease of REE, increase of total daily physical activity, decrease of IL-6 and tumor necrosis factor-?
Positive_regulation (increase) of Negative_regulation (decrease) of IL-6 associated with stress, necrosis, cancer and syndrome
4) Confidence 0.13 Published 2010 Journal Indian Journal of Palliative Care Section Body Doc Link PMC3012235 Disease Relevance 0.94 Pain Relevance 0.07
In non-CF tracheal xenografts, FP treatment before LPS stimulation induced a significant decrease in hIL-6 and hGRO-alpha.
Positive_regulation (induced) of Negative_regulation (decrease) of hIL-6 associated with fibrosis
5) Confidence 0.00 Published 2002 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12183675 Disease Relevance 1.79 Pain Relevance 0.98

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox