INT65003

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Context Info
Confidence 0.37
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.45
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ace) peptidase activity (Ace) extracellular space (Ace)
extracellular region (Ace) plasma membrane (Ace)
Anatomy Link Frequency
urinary bladder 3
heart 2
plasma 1
Ace (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 3 99.98 Very High Very High Very High
Inflammation 23 90.00 High High
cytokine 9 74.32 Quite High
tolerance 4 69.32 Quite High
chemokine 4 51.68 Quite High
Inflammatory response 3 46.28 Quite Low
bradykinin 5 32.56 Quite Low
anesthesia 3 25.00 Low Low
Catecholamine 2 11.96 Low Low
fibrosis 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nephritis 1 98.44 Very High Very High Very High
Ureteral Obstruction 1 98.16 Very High Very High Very High
Myocardial Infarction 100 98.04 Very High Very High Very High
Coronary Artery Disease 23 97.34 Very High Very High Very High
Diabetic Cardiomyopathies 105 95.20 Very High Very High Very High
Hypertension 10 93.60 High High
Heart Rate Under Development 5 92.48 High High
Cardiovascular Disease 1 91.92 High High
Chronic Renal Failure 1 90.16 High High
INFLAMMATION 25 90.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both plasma and urinary bladder tissue ANG-(1-8) levels decreased significantly following ACE inhibition, but only with ramiprilat.
Negative_regulation (decreased) of Negative_regulation (inhibition) of ACE in urinary bladder
1) Confidence 0.37 Published 1996 Journal Am. J. Kidney Dis. Section Abstract Doc Link 8840953 Disease Relevance 0 Pain Relevance 0
Angiotensin receptor blocker versus ACE inhibitor
Negative_regulation (blocker) of Negative_regulation (inhibitor) of ACE
2) Confidence 0.35 Published 2007 Journal Vascular Health and Risk Management Section Body Doc Link PMC2291334 Disease Relevance 1.06 Pain Relevance 0
Morrissey and Klahr showed that ACE inhibition decreased NF-?
Negative_regulation (decreased) of Negative_regulation (inhibition) of ACE
3) Confidence 0.17 Published 2002 Journal BMC Cardiovasc Disord Section Body Doc Link PMC65512 Disease Relevance 1.13 Pain Relevance 0.11
Both plasma and urinary bladder tissue ANG-(1-8) levels decreased significantly following ACE inhibition, but only with ramiprilat.
Negative_regulation (decreased) of in plasma Negative_regulation (inhibition) of ACE in urinary bladder
4) Confidence 0.13 Published 1996 Journal Am. J. Kidney Dis. Section Abstract Doc Link 8840953 Disease Relevance 0 Pain Relevance 0
A randomized, double-blind, active-controlled clinical trial reached to determine whether the combined incidence of fatal coronary heart disease and nonfatal myocardial infarction differs between diuretic treatment (chlorthalidone) and 3 alternative therapies: calcium channel blockers (amlodipine), ACE inhibitors (lisinopril), and ?
Negative_regulation (blockers) of Negative_regulation (inhibitors) of ACE in heart associated with coronary artery disease, calcium channel and myocardial infarction
5) Confidence 0.10 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2964943 Disease Relevance 1.26 Pain Relevance 0.13

General Comments

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