INT65014

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Context Info
Confidence 0.45
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0.42
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SOS1) extracellular space (IL6) signal transduction (SOS1)
aging (IL6) extracellular region (IL6) intracellular (SOS1)
Anatomy Link Frequency
HGF 6
SOS1 (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 6 96.48 Very High Very High Very High
Inflammatory mediators 3 95.36 Very High Very High Very High
cINOD 3 84.96 Quite High
Inflammation 3 60.16 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 6 95.36 Very High Very High Very High
Periodontal Disease 3 82.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the combination of IL gamma beta and PGE2 induced a synergistic rise in IL-6 production by HGF.
HGF Positive_regulation (rise) of Gene_expression (production) of IL-6 in HGF
1) Confidence 0.45 Published 1996 Journal J. Clin. Periodontol. Section Abstract Doc Link 8841895 Disease Relevance 0.16 Pain Relevance 0.23
Interestingly, the combination of IL gamma beta and PGE2 induced a synergistic rise in IL-6 production by HGF.
HGF Positive_regulation (induced) of Gene_expression (production) of IL-6 in HGF
2) Confidence 0.45 Published 1996 Journal J. Clin. Periodontol. Section Abstract Doc Link 8841895 Disease Relevance 0.16 Pain Relevance 0.23
Recent studies suggest that monocytic products, such as interleukin (IL)-1 beta, could stimulate IL-6 production by human gingival fibroblasts (HGF).
HGF Positive_regulation (stimulate) of Gene_expression (production) of IL-6 in HGF
3) Confidence 0.45 Published 1996 Journal J. Clin. Periodontol. Section Abstract Doc Link 8841895 Disease Relevance 0.10 Pain Relevance 0.14

General Comments

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