INT65093

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.56
First Reported 1996
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 2.10
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ACP5) small molecule metabolic process (ACP5) lysosome (ACP5)
Anatomy Link Frequency
mandible 1
macrophages 1
multinucleated giant cells 1
osteoclasts 1
ACP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Catecholamine 7 99.12 Very High Very High Very High
Clonidine 1 97.04 Very High Very High Very High
cOX1 2 96.56 Very High Very High Very High
Paresthesia 2 94.72 High High
Pain 5 93.20 High High
Inflammation 10 81.24 Quite High
cva 1 78.12 Quite High
Snapping jaw 2 50.00 Quite Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 6 99.08 Very High Very High Very High
Calcifying Odontogenic Cyst 2 96.04 Very High Very High Very High
Pressure And Volume Under Development 2 93.28 High High
Hypercalcemia 4 86.52 High High
Calcification 3 86.52 High High
Pain 1 83.36 Quite High
Disease 3 82.32 Quite High
INFLAMMATION 12 81.24 Quite High
Tendinopathy 2 78.88 Quite High
Hemorrhage 1 78.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Catecholamines also reduced cell proliferation, increased tartrate-resistant acid phosphatase (TRAcP) activity, interleukin 6 (IL-6) production, multi-nuclearity and response to salmon calcitonin (sCT) in undifferentiated FLG 29.1 cells.
Gene_expression (production) of tartrate-resistant acid phosphatase associated with catecholamine
1) Confidence 0.56 Published 1996 Journal Osteoporos Int Section Abstract Doc Link 8845594 Disease Relevance 0 Pain Relevance 0.39
Ghost cell odontogenic carcinoma of the mandible: a case report demonstrating expression of tartrate-resistant acid phosphatase (TRAP) and vitronectin receptor.
Gene_expression (expression) of tartrate-resistant acid phosphatase in mandible associated with carcinoma
2) Confidence 0.56 Published 2008 Journal J Craniomaxillofac Surg Section Title Doc Link 18674923 Disease Relevance 0.39 Pain Relevance 0.14
Although it often causes irregular destruction of the adjacent bone, immunohistochemical expression of tartrate-resistant acid phosphatase (TRAP) and vitronectin receptor has not previously been described in this carcinoma.
Gene_expression (expression) of tartrate-resistant acid phosphatase associated with carcinoma
3) Confidence 0.56 Published 2008 Journal J Craniomaxillofac Surg Section Abstract Doc Link 18674923 Disease Relevance 0.45 Pain Relevance 0.14
These multinucleated giant cells were positive for tartrate-resistant acid phosphatase (TRAP) and had the ability to absorb bone.
Gene_expression (positive) of tartrate-resistant acid phosphatase in multinucleated giant cells
4) Confidence 0.50 Published 2007 Journal Osteoarthr. Cartil. Section Body Doc Link 16979913 Disease Relevance 0 Pain Relevance 0
OPN was localized in two distinct cell types, i.e., fibroblast-like cells negative for CD68 and tartrate-resistant acid phosphatase (TRAP) and multinucleated macrophages positive for CD68 and TRAP.
Neg (negative) Gene_expression (negative) of tartrate-resistant acid phosphatase in macrophages
5) Confidence 0.49 Published 2001 Journal Virchows Arch. Section Abstract Doc Link 11469694 Disease Relevance 0.39 Pain Relevance 0.14
This finding is consistent with the eEPC transcriptome profile that indicated high expression of lysosome enzymes such as lysozyme (LYZ), cathepsins (CTSB, CTSD, CTSH, CTSL1), acid phosphatase (ACP2, ACP5), acid lipase (LIPA), and ?
Gene_expression (expression) of ACP5
6) Confidence 0.30 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC2881111 Disease Relevance 0 Pain Relevance 0
Cultured osteoclasts are multinucleated, express tartrate resistant acid phosphatase (TRAP), form F-actin rings and resorb bone.
Gene_expression (express) of tartrate resistant acid phosphatase in osteoclasts
7) Confidence 0.23 Published 2002 Journal Res. Vet. Sci. Section Abstract Doc Link 12443687 Disease Relevance 0.32 Pain Relevance 0.08
This analysis revealed statistically significant differential expression for only three genes; tartrate resistant acid phosphatase 5 (ACP5) increased by a fold change of 10.60 (5 to 53 ESTs), cytochrome c oxidase subunit I (COX1) increased by a fold change of 2.1 (87 to 178 ESTs), and perlecan decreased by a fold change of 3.9 (31 to 8 ESTs).
Gene_expression (expression) of ACP5 associated with cox1
8) Confidence 0.17 Published 2006 Journal BMC Genomics Section Body Doc Link PMC1578570 Disease Relevance 0.56 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox