INT6511

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Context Info
Confidence 0.70
First Reported 1984
Last Reported 2010
Negated 4
Speculated 0
Reported most in Abstract
Documents 76
Total Number 76
Disease Relevance 70.15
Pain Relevance 7.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (AFP) extracellular space (AFP) extracellular region (AFP)
cytoplasm (AFP)
Anatomy Link Frequency
liver 9
CSF 4
scapula 2
globules 2
blood 2
AFP (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 100.00 Very High Very High Very High
palliative 7 99.76 Very High Very High Very High
pain flank 2 99.08 Very High Very High Very High
abdominal pain 30 98.88 Very High Very High Very High
imagery 46 98.24 Very High Very High Very High
anesthesia 5 97.52 Very High Very High Very High
Pain 24 97.48 Very High Very High Very High
alcohol 3 96.64 Very High Very High Very High
Bile 3 95.36 Very High Very High Very High
headache 18 94.88 High High
Disease Link Frequency Relevance Heat
Cancer 407 100.00 Very High Very High Very High
Paralysis 107 100.00 Very High Very High Very High
Cirrhosis 41 99.96 Very High Very High Very High
Solid Tumor 2 99.92 Very High Very High Very High
Anaemia 2 99.90 Very High Very High Very High
Hypoalbuminemia 1 99.84 Very High Very High Very High
Endodermal Sinus Tumor 26 99.76 Very High Very High Very High
Metastasis 213 99.72 Very High Very High Very High
Rhinitis 5 99.72 Very High Very High Very High
Cyst 26 99.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We report herein the case of a 65-year-old man with cirrhosis of the liver in whom a portal vein thrombus was found to be the cause of a marked elevation in serum alpha-fetoprotein (AFP).
Positive_regulation (elevation) of AFP in portal vein associated with cirrhosis and thrombosis
1) Confidence 0.70 Published 1996 Journal Surg. Today Section Abstract Doc Link 8897683 Disease Relevance 0.73 Pain Relevance 0.13
An examination revealed that his alpha-fetoprotein (AFP) was elevated (3319 ng/ml).
Positive_regulation (elevated) of alpha-fetoprotein
2) Confidence 0.70 Published 1988 Journal Gan No Rinsho Section Abstract Doc Link 2451763 Disease Relevance 0.87 Pain Relevance 0.10
An examination revealed that his alpha-fetoprotein (AFP) was elevated (3319 ng/ml).
Positive_regulation (elevated) of AFP
3) Confidence 0.70 Published 1988 Journal Gan No Rinsho Section Abstract Doc Link 2451763 Disease Relevance 0.86 Pain Relevance 0.10
Laboratory tests showed markedly increased alpha-fetoprotein (AFP) level (600 ng/ml) and tomography demonstrated osteolytic lesion of the 5th lumbar vertebra and right scapula.
Positive_regulation (increased) of alpha-fetoprotein in scapula
4) Confidence 0.70 Published 1984 Journal Hinyokika Kiyo Section Abstract Doc Link 6209970 Disease Relevance 0.49 Pain Relevance 0.10
We report herein the case of a 65-year-old man with cirrhosis of the liver in whom a portal vein thrombus was found to be the cause of a marked elevation in serum alpha-fetoprotein (AFP).
Positive_regulation (elevation) of alpha-fetoprotein in portal vein associated with cirrhosis and thrombosis
5) Confidence 0.70 Published 1996 Journal Surg. Today Section Abstract Doc Link 8897683 Disease Relevance 0.73 Pain Relevance 0.13
Laboratory tests showed markedly increased alpha-fetoprotein (AFP) level (600 ng/ml) and tomography demonstrated osteolytic lesion of the 5th lumbar vertebra and right scapula.
Positive_regulation (increased) of AFP in scapula
6) Confidence 0.70 Published 1984 Journal Hinyokika Kiyo Section Abstract Doc Link 6209970 Disease Relevance 0.49 Pain Relevance 0.10
In addition, serum alpha-fetoprotein (AFP) levels were elevated.
Positive_regulation (elevated) of AFP
7) Confidence 0.70 Published 2000 Journal J. Neurosurg. Section Abstract Doc Link 11014548 Disease Relevance 0.63 Pain Relevance 0.09
He had a history of chronic hepatitis C, but HCV-RNA was negative and AFP and PIVKA-II were not elevated.
Neg (not) Positive_regulation (elevated) of AFP associated with chronic hepatitis and hepatitis c virus infection
8) Confidence 0.70 Published 2007 Journal Nippon Shokakibyo Gakkai Zasshi Section Abstract Doc Link 17611384 Disease Relevance 0.90 Pain Relevance 0.07
At that time, the serum alpha-fetoprotein (AFP) level increased to 23,036 ng/ml, but the level of serum beta-subunit of human chorionic gonadotropin was less than 0.2 ng/ml.
Positive_regulation (increased) of AFP
9) Confidence 0.69 Published 1990 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 1701859 Disease Relevance 0.73 Pain Relevance 0.12
Elevation of human chorionic gonadotrophin (HCG) and alpha-fetoprotein (AFP) in both serum and cerebrospinal fluid (CSF) was observed.
Positive_regulation (Elevation) of AFP in CSF
10) Confidence 0.68 Published 1994 Journal No Shinkei Geka Section Abstract Doc Link 8078594 Disease Relevance 1.30 Pain Relevance 0.08
The elevated HCG and AFP levels in serum and CSF returned to their normal range within 2 months after surgery.
Positive_regulation (elevated) of AFP in CSF
11) Confidence 0.68 Published 1994 Journal No Shinkei Geka Section Abstract Doc Link 8078594 Disease Relevance 1.01 Pain Relevance 0.05
Elevation of human chorionic gonadotrophin (HCG) and alpha-fetoprotein (AFP) in both serum and cerebrospinal fluid (CSF) was observed.
Positive_regulation (Elevation) of alpha-fetoprotein in CSF
12) Confidence 0.68 Published 1994 Journal No Shinkei Geka Section Abstract Doc Link 8078594 Disease Relevance 1.29 Pain Relevance 0.08
Serum levels of alpha-fetoprotein and human chorionic gonadotropin were found to be elevated at 920.2 microg/l and 637.4 U/l, respectively.
Positive_regulation (elevated) of alpha-fetoprotein
13) Confidence 0.68 Published 2008 Journal Nature clinical practice. Urology Section Abstract Doc Link 18268549 Disease Relevance 1.00 Pain Relevance 0.09
However, many liver diseases also frequently show the elevation of AFP.
Positive_regulation (elevation) of AFP in liver associated with liver disease
14) Confidence 0.68 Published 1994 Journal Hinyokika Kiyo Section Abstract Doc Link 7514845 Disease Relevance 0.67 Pain Relevance 0.08
Blood tests showed elevated alpha-fetal protein (AFP) level of 458 ng/ml.
Positive_regulation (elevated) of AFP in Blood
15) Confidence 0.67 Published 2008 Journal World J Surg Oncol Section Body Doc Link PMC2373298 Disease Relevance 1.75 Pain Relevance 0.05
The patient had anemia and elevated serum alpha-fetoprotein (AFP) (9630ng/mL) and PIVKA-II (91mAU/mL) levels.
Positive_regulation (elevated) of AFP associated with anaemia
16) Confidence 0.67 Published 2005 Journal Hepatogastroenterology Section Abstract Doc Link 16334809 Disease Relevance 1.02 Pain Relevance 0.10
Based on the findings of elevated serum alpha-feto protein (AFP, 245 ng/ml) and normal carcino-embryonic antigen (CEA, 2.6 ng/ml) levels, a preoperative diagnosis of hepatocellular carcinoma was made.
Positive_regulation (elevated) of AFP associated with hepatocellular cancer
17) Confidence 0.67 Published 1998 Journal J. Gastroenterol. Section Abstract Doc Link 9719250 Disease Relevance 1.70 Pain Relevance 0.13
Cirrhosis, elevated alpha-fetoprotein levels, and risk factors for HCC such as viral hepatitis are typically absent.
Positive_regulation (elevated) of alpha-fetoprotein associated with cirrhosis, hepatocellular cancer and hepatitis virus infection
18) Confidence 0.67 Published 2007 Journal Ann Ital Chir Section Abstract Doc Link 17518332 Disease Relevance 1.61 Pain Relevance 0.06
The majority had cirrhosis of the liver, were positive for markers of hepatitis B virus, and showed elevated serum alpha fetoprotein (AFP).
Positive_regulation (elevated) of AFP in liver associated with cirrhosis and hepatitis
19) Confidence 0.67 Published 1992 Journal Int Surg Section Abstract Doc Link 1336000 Disease Relevance 1.00 Pain Relevance 0.10
The pregnancy had been remarkable for an elevated alpha-fetoprotein level (2.86 multiples of the median (MoM)) as part of the maternal serum screen drawn in the 18th week of gestation.
Positive_regulation (elevated) of alpha-fetoprotein in MoM
20) Confidence 0.67 Published 2007 Journal J Med Case Reports Section Body Doc Link PMC1948010 Disease Relevance 0.48 Pain Relevance 0.05

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