INT65179

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Context Info
Confidence 0.07
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.37
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gria1) endoplasmic reticulum (Gria1) plasma membrane (Gria1)
protein complex (Gria1)
Anatomy Link Frequency
brain 2
Gria1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 131 100.00 Very High Very High Very High
Glutamate receptor 8 100.00 Very High Very High Very High
Nucleus accumbens 5 96.52 Very High Very High Very High
antagonist 24 94.24 High High
dopamine receptor 1 93.80 High High
long-term potentiation 26 92.32 High High
depression 9 91.52 High High
Calcium channel 1 88.04 High High
Hippocampus 69 81.20 Quite High
Enkephalin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Depression 9 91.52 High High
Aging 114 74.08 Quite High
Body Weight 1 68.60 Quite High
Cognitive Disorder 25 66.40 Quite High
Urological Neuroanatomy 14 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Sprains And Strains 7 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 3 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The data demonstrate that the acute effects of glutamate receptor activity on striatal and accumbal PPE mRNA expression via the NMDA receptor can be modulated by the dopaminergic system in the brain of the rat.
Regulation (modulated) of Regulation (effects) of glutamate receptor in brain associated with nmda receptor and glutamate receptor
1) Confidence 0.07 Published 1996 Journal Neurosci. Lett. Section Abstract Doc Link 8848257 Disease Relevance 0.07 Pain Relevance 0.55
The interpretation of these changes in NMDA receptor functions are complicated by alterations in the regulation of calcium and metabotropic glutamate receptor activity in the same region (Norris et al., 1998; Kumar and Foster, 2004, 2007).
Regulation (alterations) of Regulation (regulation) of glutamate receptor associated with glutamate receptor and nmda receptor
2) Confidence 0.01 Published 2010 Journal Frontiers in Aging Neuroscience Section Body Doc Link PMC2874396 Disease Relevance 0.30 Pain Relevance 0.84

General Comments

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