INT65190

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Context Info
Confidence 0.44
First Reported 1996
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.51
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Umod) extracellular region (Umod) Golgi apparatus (Umod)
cytoplasmic membrane-bounded vesicle (Umod) plasma membrane (Umod)
Anatomy Link Frequency
tail 1
Umod (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Antinociceptive 1 99.98 Very High Very High Very High
antagonist 2 99.40 Very High Very High Very High
tail-flick 5 98.52 Very High Very High Very High
Spinal cord 8 95.40 Very High Very High Very High
Pain 4 89.88 High High
Neurotransmitter 1 87.96 High High
Pain threshold 2 80.08 Quite High
Intracerebroventricular 1 73.76 Quite High
GABAergic 1 73.68 Quite High
Analgesic 1 68.40 Quite High
Disease Link Frequency Relevance Heat
Pain 6 89.88 High High
Nociception 1 69.76 Quite High
Anxiety Disorder 1 67.36 Quite High
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The alkaloid strychnine, well-known as a glycine receptor (Gly-R) antagonist, blocked glycine stimulatory effect on 3alpha,5alpha-THP formation.
Regulation (effect) of THP associated with antagonist
1) Confidence 0.44 Published 2008 Journal Neuroscience Section Abstract Doc Link 18367344 Disease Relevance 0.07 Pain Relevance 0.52
In particular, EB potentiated the antinociceptive effect of THP and DHP by significantly increasing tail-flick latencies above those of non-EB-treated animals.
Regulation (effect) of THP in tail associated with tail-flick and antinociceptive
2) Confidence 0.08 Published 1996 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 8848456 Disease Relevance 0.44 Pain Relevance 0.75

General Comments

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