INT6520

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Context Info
Confidence 0.44
First Reported 1981
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.15
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ADRA1D) plasma membrane (ADRA1D) cell-cell signaling (ADRA1D)
DNA metabolic process (ADRA1D) signal transducer activity (ADRA1D)
Anatomy Link Frequency
plasma 2
ergot 2
blood cells 2
ADRA1D (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 1 100.00 Very High Very High Very High
agonist 1 99.70 Very High Very High Very High
ergotamine 3 98.90 Very High Very High Very High
antagonist 1 98.68 Very High Very High Very High
Migraine 1 98.12 Very High Very High Very High
Clonidine 2 95.80 Very High Very High Very High
epidural 4 92.68 High High
analgesia 4 92.32 High High
Chronic pancreatitis 2 68.16 Quite High
depression 1 61.68 Quite High
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 7 100.00 Very High Very High Very High
Hemorrhage 1 100.00 Very High Very High Very High
Headache 1 98.12 Very High Very High Very High
Pancreatic Cancer 10 97.24 Very High Very High Very High
Pancreatitis 2 68.16 Quite High
Cancer 2 65.12 Quite High
Depression 1 61.68 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Postoperative changes in various haemostatic parameters (capillary bleeding time, platelet count, fibrinogen, fibrinmonomers, prothrombin, antithrombin III, factor VIII procoagulant, factor VIII antigen, euglobulin clot lysis time, streptokinase lysis time, fibrinogen related antigens, alpha 1-antitrypsin and alpha 2-macroglobulin) plasma glucose and cortisol were studied in 12 female patients undergoing elective abdominal hysterectomy during either general anaesthesia or epidural analgesia (T4-S5).
Regulation (changes) of Gene_expression (procoagulant) of alpha 1 in plasma associated with epidural, hemorrhage and analgesia
1) Confidence 0.44 Published 1981 Journal Br J Surg Section Abstract Doc Link 7225737 Disease Relevance 0.16 Pain Relevance 0.49
alpha1,4-N-Acetylglucosaminyltransferase (alpha4GnT) is a glycosyltransferase responsible for the biosynthesis of alpha1,4-GlcNAc-capped O-glycans, and is frequently expressed in pancreatic cancer cells but not peripheral blood cells.
Regulation (responsible) of Gene_expression (biosynthesis) of alpha1 in blood cells associated with pancreatic cancer
2) Confidence 0.44 Published 2006 Journal Cancer Sci. Section Abstract Doc Link 16441422 Disease Relevance 0.45 Pain Relevance 0.07
INTRODUCTION: Ergotamine, an ergot alkaloid with partial agonist effects on alpha1 receptors and serotonin receptors, is widely used in the treatment of migraine.
Regulation (effects) of Gene_expression (receptors) of alpha1 in ergot associated with migraine, agonist, serotonin and ergotamine
3) Confidence 0.44 Published 2008 Journal Clin Toxicol (Phila) Section Abstract Doc Link 18763151 Disease Relevance 0.17 Pain Relevance 0.33
In contrast, cooling abolished alpha 1-adrenergic vasoconstriction produced by phenylephrine, which was not affected by yohimbine.
Neg (not) Regulation (affected) of Gene_expression (produced) of alpha 1-adrenergic associated with increased venous pressure under development
4) Confidence 0.19 Published 1992 Journal Am. J. Physiol. Section Abstract Doc Link 1329562 Disease Relevance 0.36 Pain Relevance 0.23
[The effect of oxytocin stimulation on PGE2, 6keto PGF1 alpha production in human myometrial monolayer culture].
Regulation (effect) of Gene_expression (production) of PGF1 alpha
5) Confidence 0.02 Published 1993 Journal Nippon Sanka Fujinka Gakkai Zasshi Section Title Doc Link 8315315 Disease Relevance 0 Pain Relevance 0.06

General Comments

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