INT65207

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.70
First Reported 1996
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 10
Disease Relevance 3.50
Pain Relevance 2.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fgf2) extracellular space (Fgf2) extracellular region (Fgf2)
nucleus (Fgf2) embryo development (Fgf2) cytoplasm (Fgf2)
Anatomy Link Frequency
nucleus 4
fibroblast 4
hippocampus 3
spinal cord 2
HGF 2
Fgf2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 66 100.00 Very High Very High Very High
Sciatic nerve 9 97.52 Very High Very High Very High
antidepressant 12 96.80 Very High Very High Very High
Hippocampus 14 94.80 High High
fluoxetine 6 90.16 High High
Desipramine 6 89.44 High High
Central nervous system 35 85.96 High High
Substantia nigra 4 82.00 Quite High
Pain 2 80.12 Quite High
dexamethasone 2 79.44 Quite High
Disease Link Frequency Relevance Heat
Spinal Cord Injury 33 100.00 Very High Very High Very High
Aids-related Complex 10 99.80 Very High Very High Very High
Brain Injury 1 99.08 Very High Very High Very High
Retinal Degeneration 29 98.56 Very High Very High Very High
Head Trauma 7 97.96 Very High Very High Very High
Injury 54 94.72 High High
Sprains And Strains 9 94.72 High High
Bone Fracture 4 91.52 High High
Paralysis 22 86.80 High High
Apoptosis 45 84.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We should emphasize that based on the results presented in this report, the functional electrical stimulation led to elevation of FGF-2 mainly in the cytoplasm of neurons of facial nucleus, which differed to the findings of systemic corticosterone that promoted elevation of FGF-2 in the nuclei of astrocytes of facial nucleus.
Positive_regulation (promoted) of Positive_regulation (elevation) of FGF-2 in nucleus
1) Confidence 0.70 Published 2010 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2995486 Disease Relevance 0.09 Pain Relevance 0
The increase in FGF2 mRNA after a single injection was seen only at 5 h after the injection and was restricted to the entorhinal cortex, whereas the effect of the long-term treatments lasted up to 24 h and occurred in the entire cortex and hippocampus.
Positive_regulation (restricted) of Positive_regulation (increase) of FGF2 mRNA in hippocampus associated with hippocampus
2) Confidence 0.50 Published 2002 Journal Mol. Pharmacol. Section Abstract Doc Link 11961119 Disease Relevance 0 Pain Relevance 0.78
We have shown in this study that systemic corticosterone for 7 days led to upregulation of FGF-2 immunoreactivity mainly in astrocytes of rat facial nucleus.
Positive_regulation (led) of Positive_regulation (upregulation) of FGF-2 in nucleus
3) Confidence 0.47 Published 2010 Journal J Brachial Plex Peripher Nerve Inj Section Body Doc Link PMC2995486 Disease Relevance 0.29 Pain Relevance 0.18
In the present study, nilvadipine-induced enhancement of the endogenous FGF-2 and Arc expressions were also recognized in P23H model.
Positive_regulation (induced) of Positive_regulation (enhancement) of FGF-2 associated with aids-related complex
4) Confidence 0.44 Published 2008 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2699806 Disease Relevance 0.65 Pain Relevance 0.04
Thus, a posttraumatic increase of the serum bFGF was induced by bone as well as by brain injury, but was not causally related with the growth-promoting effects of the sera, as was proven by an in vitro analysis of the effects of the patients sera on L929 fibroblast growth.
Positive_regulation (induced) of Positive_regulation (increase) of bFGF in fibroblast associated with brain injury
5) Confidence 0.37 Published 1996 Journal Unfallchirurg Section Abstract Doc Link 8850075 Disease Relevance 1.03 Pain Relevance 0
Danshen activated the FGF-signaling pathway as evidenced by increased levels of FGF-2 and uPA.
Positive_regulation (increased) of Positive_regulation (levels) of FGF-2
6) Confidence 0.36 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2997511 Disease Relevance 0 Pain Relevance 0.05
Recently, it is also reported that elevation of both FGF2 and CNTF level after spinal cord injury induces development of oligodendrocytes [54].
Positive_regulation (induces) of Positive_regulation (elevation) of FGF2 in spinal cord associated with spinal cord
7) Confidence 0.33 Published 2009 Journal Mol Brain Section Body Doc Link PMC2789715 Disease Relevance 0.19 Pain Relevance 0.15
Also increasing concentrations of basic fibroblast growth factor (bFGF) resulted in a significant increase of EPC cell number with a maximal effect observed between 10 ?
Positive_regulation (resulted) of Positive_regulation (increasing) of bFGF in fibroblast
8) Confidence 0.22 Published 2007 Journal Respir Res Section Body Doc Link PMC2000890 Disease Relevance 0 Pain Relevance 0
The increase in FGF2 mRNA after a single injection was seen only at 5 h after the injection and was restricted to the entorhinal cortex, whereas the effect of the long-term treatments lasted up to 24 h and occurred in the entire cortex and hippocampus.
Positive_regulation (restricted) of in cortex Positive_regulation (increase) of FGF2 mRNA in hippocampus associated with hippocampus
9) Confidence 0.17 Published 2002 Journal Mol. Pharmacol. Section Abstract Doc Link 11961119 Disease Relevance 0 Pain Relevance 0.78
A number of growth factors play a specific role in regeneration and it has been proven that a previously described method of physically and chemically stimulating whole blood (to produce autologous conditioned serum) induces concentration increases in FGF-2, HGF, and TGF-beta1.
Positive_regulation (induces) of Positive_regulation (increases) of FGF-2 in HGF
10) Confidence 0.07 Published 2004 Journal Int J Sports Med Section Abstract Doc Link 15532001 Disease Relevance 1.27 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox