INT65375

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Context Info
Confidence 0.67
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 1.71
Pain Relevance 0.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CCKBR) plasma membrane (CCKBR) nucleus (CCKBR)
cytoplasm (CCKBR) signal transducer activity (CCKBR)
Anatomy Link Frequency
ear 1
neural 1
CCKBR (Homo sapiens)
Pain Link Frequency Relevance Heat
Cholecystokinin 6 96.24 Very High Very High Very High
tetrodotoxin 1 83.88 Quite High
antagonist 3 65.12 Quite High
imagery 45 61.20 Quite High
Calcium channel 15 5.00 Very Low Very Low Very Low
medulla 9 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
midbrain 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
amygdala 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Tinnitus 288 99.96 Very High Very High Very High
Deafness 45 98.28 Very High Very High Very High
Anxiety Disorder 27 94.52 High High
Hyperacusis 9 68.04 Quite High
Death 3 5.00 Very Low Very Low Very Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Aging 3 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 5.00 Very Low Very Low Very Low
Peripheral Arterial Disease 3 5.00 Very Low Very Low Very Low
Brain Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In antrum, activation of neural CCKA or CCKB receptors initiates contractions.
Positive_regulation (activation) of CCKB in neural
1) Confidence 0.67 Published 1996 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 8859008 Disease Relevance 0 Pain Relevance 0.27
After salicylate treatment, gASR startle amplitude was significantly increased at 12 kHz (12%±3.85; p?
Positive_regulation (increased) of gASR
2) Confidence 0.16 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3002264 Disease Relevance 0.15 Pain Relevance 0
The fact that only one functional ear is necessary for pASR and gASR tinnitus assessment has previously been reported [17].
Positive_regulation (necessary) of gASR in ear associated with tinnitus
3) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3002264 Disease Relevance 0.98 Pain Relevance 0
However, the salicylate group showed a decreased ability to inhibit gASR one hour after salicylate treatment, but by seven hours the ability to attenuate gASR had returned to normal levels.
Positive_regulation (attenuate) of gASR
4) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3002264 Disease Relevance 0.59 Pain Relevance 0.03

General Comments

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