INT65642

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Context Info
Confidence 0.41
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 27
Total Number 27
Disease Relevance 15.83
Pain Relevance 2.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Dync1h1) Golgi apparatus (Dync1h1) ATPase activity (Dync1h1)
cytoskeleton (Dync1h1) cytoplasm (Dync1h1)
Anatomy Link Frequency
blood 2
proximal 2
lower limbs 2
piles 1
palpebral conjunctiva 1
Dync1h1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 61 100.00 Very High Very High Very High
cva 136 98.60 Very High Very High Very High
Analgesic 15 98.56 Very High Very High Very High
colic 4 97.12 Very High Very High Very High
Piles 13 92.74 High High
alcohol 72 91.36 High High
diclofenac 3 86.48 High High
headache 35 84.04 Quite High
aspirin 12 79.72 Quite High
analgesia 6 75.00 Quite High
Disease Link Frequency Relevance Heat
Infection 199 100.00 Very High Very High Very High
Pain 57 100.00 Very High Very High Very High
Arrhythmia Under Development 1 99.92 Very High Very High Very High
Sprains And Strains 30 99.86 Very High Very High Very High
Renal Disease 48 99.72 Very High Very High Very High
Shock 65 99.70 Very High Very High Very High
Pressure And Volume Under Development 132 98.96 Very High Very High Very High
Malaria 59 98.90 Very High Very High Very High
Cv General 3 Under Development 114 98.60 Very High Very High Very High
Sleep Disorders 6 98.60 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SWL without ECG triggering was not associated with the occurrence of dysrhythmic episodes of any particular clinical significance.
SWL Binding (associated) of
1) Confidence 0.41 Published 2008 Journal Arch Ital Urol Androl Section Abstract Doc Link 18533621 Disease Relevance 0.25 Pain Relevance 0.10
BACKGROUND: The development of newer-generation lithotripters has reduced the pain associated with SWL, but many patients still require some form of sedation.
SWL Binding (associated) of associated with pain and sleep disorders
2) Confidence 0.35 Published 1999 Journal J. Endourol. Section Abstract Doc Link 10479002 Disease Relevance 0.20 Pain Relevance 0.36
The patients who underwent RPPL were up and about, performing their daily chores usually in one day’s time, whereas, patients who underwent SWL had pain after each sitting and due to multiple sittings took a longer time to resume normal activities.
SWL Binding (pain) of associated with pain
3) Confidence 0.32 Published 2010 Journal Journal of Minimal Access Surgery Section Body Doc Link PMC2992658 Disease Relevance 0.16 Pain Relevance 0.34
Those regions are highly endemic for Loa Loa.
Loa Binding (endemic) of
4) Confidence 0.32 Published 2002 Journal Bull Soc Belge Ophtalmol Section Abstract Doc Link 12058486 Disease Relevance 0.46 Pain Relevance 0.07
We retrospectively evaluated 224 consecutive patients who underwent SWL (n=156) or URS (n=68) for a single, primary, radiopaque proximal ureteral stone between January 2004 and July 2009 at our institute.
SWL Binding (underwent) of in proximal
5) Confidence 0.32 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2991578 Disease Relevance 0 Pain Relevance 0.07
We assessed patient perception with our specifically tailored questionnaire because several validated questionnaires for general QoL are not enough to discriminate satisfaction in patients undergoing URS or SWL for proximal ureteral stones.
SWL Binding (undergoing) of in proximal
6) Confidence 0.32 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2991578 Disease Relevance 0 Pain Relevance 0
There was minimal morbidity associated with SWL in either group.
SWL Binding (associated) of
7) Confidence 0.31 Published 1996 Journal J. Endourol. Section Abstract Doc Link 8872731 Disease Relevance 0.52 Pain Relevance 0.24
This was confirmed during open ureterolithotomy procedures where it was found that the stone was completely fragmented with SWL but the fragments were not cleared due to edema of surrounding mucosa.
SWL Binding (fragmented) of associated with pressure and volume under development
8) Confidence 0.31 Published 2008 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2684398 Disease Relevance 0.25 Pain Relevance 0
This is probably explained by the existence in the human population of a positive association between Loa and M. perstans infections [37,38].
Loa Binding (association) of associated with infection
9) Confidence 0.30 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 0.68 Pain Relevance 0
Additional data are required to document the possible interactions between Loa loa and Trypanosoma, and to evaluate whether the co-infected patients would have to be treated by ivermectin.


loa Binding (interactions) of
10) Confidence 0.30 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 0.70 Pain Relevance 0.11
We studied the outcome of SWL monotherapy in patients with solitary renal stones greater than 2 cm who opted for it after knowing the various options of treatment.


SWL Binding (outcome) of
11) Confidence 0.30 Published 2010 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2978434 Disease Relevance 0.51 Pain Relevance 0
These attempts at experimental infection of a human being with simian Loa are as follows:
Loa Binding (being) of associated with infection
12) Confidence 0.29 Published 2004 Journal Filaria J Section Body Doc Link PMC514527 Disease Relevance 0.85 Pain Relevance 0
As the frequency of the lithotripter increases, there is less time for these bubbles to spread, and they form bubble piles by joining with each other as described by Huber and Zeman.23-25 Because of this effect, slowing the shock wave rate would allow bubbles to dissipate and erode the stone before the arrival of new bubbles with a new shock wave, thus facilitating stone fragmentation.18,23 In vitro and animal studies have shown that reducing the frequency of shocks increased the efficiency of SWL and that the ideal frequency for effective fragmentation was 60 shocks per minute.15,17
SWL Binding (efficiency) of in piles associated with shock and piles
13) Confidence 0.27 Published 2010 Journal Clinics (Sao Paulo) Section Body Doc Link PMC2972613 Disease Relevance 0.61 Pain Relevance 0.10
Additional data are required to document the possible interactions between Loa loa and Trypanosoma, and to evaluate whether the co-infected patients would have to be treated by ivermectin.


Loa Binding (interactions) of
14) Confidence 0.27 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 0.70 Pain Relevance 0.11
One of the signs associated with the post-ivermectin Loa-related SAEs is the appearance of haemorrhages in the palpebral conjunctiva (HPC) and of retinal lesions (RL), described by Fobi et al., [8].
Loa Binding (associated) of in palpebral conjunctiva associated with cva
15) Confidence 0.25 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 0.77 Pain Relevance 0.14
Besides this, a number of authors have reported cases of patients who presented, as ours, an infection with Loa loa and a renal disease with oedema of the lower limbs [20-22].
Loa Binding (infection) of in lower limbs associated with pressure and volume under development, renal disease and infection
16) Confidence 0.24 Published 2006 Journal Filaria J Section Body Doc Link PMC1471781 Disease Relevance 1.67 Pain Relevance 0.13
In most cases, no malaria parasite was found, but in some cases high numbers of Loa microfilariae were associated with Plasmodium.
Loa Binding (associated) of associated with malaria
17) Confidence 0.23 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 1.06 Pain Relevance 0.05
Besides these signs, which are classically reported after ivermectin treatment of patients not infected with Loa loa, but at a lower degree of seriousness, more alarming signs sometimes developed as soon as D1.
loa Binding (infected) of
18) Confidence 0.23 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 1.16 Pain Relevance 0.27
Besides these signs, which are classically reported after ivermectin treatment of patients not infected with Loa loa, but at a lower degree of seriousness, more alarming signs sometimes developed as soon as D1.
Loa Binding (infected) of
19) Confidence 0.23 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 1.16 Pain Relevance 0.27
As indicated above, the Loa microfilarial loads recorded 24, 48 and 72 hours after treatment in patients who received ivermectin at a dose of 200 ?
Loa Binding (above) of
20) Confidence 0.23 Published 2003 Journal Filaria J Section Body Doc Link PMC2147657 Disease Relevance 0.15 Pain Relevance 0

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