INT65677

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Context Info
Confidence 0.25
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.29
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (FSHR) signal transduction (CGA) small molecule metabolic process (CGA)
extracellular region (CGA) plasma membrane (FSHR) cellular nitrogen compound metabolic process (CGA)
CGA (Homo sapiens)
FSHR (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 1 100.00 Very High Very High Very High
agonist 14 70.16 Quite High
Versed 1 53.76 Quite High
algil 1 52.88 Quite High
antagonist 5 41.96 Quite Low
Opioid 1 33.52 Quite Low
Pain 3 5.00 Very Low Very Low Very Low
abdominal pain 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anovulation 7 98.36 Very High Very High Very High
Endometriosis (extended) 6 75.96 Quite High
Sleep Disorders 1 54.88 Quite High
Stress 1 25.00 Low Low
Ovarian Hyperstimulation Syndrome 11 5.00 Very Low Very Low Very Low
Polycystic Ovary Syndrome 9 5.00 Very Low Very Low Very Low
Reprotox - General 2 8 5.00 Very Low Very Low Very Low
Reprotox - General 1 6 5.00 Very Low Very Low Very Low
Reprotox - General 3 5 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The use of follitropin alpha is comparable to HP FSH for ovulation induction in WHO group II anovulation.
follitropin alpha Binding (comparable) of FSH associated with anovulation
1) Confidence 0.25 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2819896 Disease Relevance 0.10 Pain Relevance 0
Genetically engineered FSH combines portions of the native protein with another protein (hCG) which enhances its potency and extends the half-life compared with wild-type FSH.
hCG Binding (extends) of FSH associated with potency
2) Confidence 0.06 Published 1996 Journal Drugs Section Abstract Doc Link 8875126 Disease Relevance 0.19 Pain Relevance 0.16

General Comments

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