INT65734

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Context Info
Confidence 0.06
First Reported 1996
Last Reported 2005
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.25
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Chi3l1) extracellular region (Chi3l1) endoplasmic reticulum (Chi3l1)
carbohydrate metabolic process (Chi3l1) molecular_function (Chi3l1) cytoplasm (Chi3l1)
Anatomy Link Frequency
tail 1
Chi3l1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 1 98.74 Very High Very High Very High
tail-flick 2 98.20 Very High Very High Very High
antagonist 1 97.00 Very High Very High Very High
allodynia 5 96.52 Very High Very High Very High
antidepressant 3 96.32 Very High Very High Very High
agonist 1 90.16 High High
antinociception 2 86.64 High High
Central grey 2 83.20 Quite High
Desipramine 2 81.32 Quite High
Antinociceptive 1 57.84 Quite High
Disease Link Frequency Relevance Heat
Nociception 4 99.64 Very High Very High Very High
Neuropathic Pain 5 96.52 Very High Very High Very High
Urological Neuroanatomy 10 93.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Acute treatment with amitryptiline (10), clorgyline (1), fluoxetine (10), nomifensine (10) or maprotiline (20) had no significant effect on [3H]CGP-12177-labelled beta-adrenoceptors, suggesting that rapid down-regulation may not be a general property of antidepressant drugs.
Neg (no) Regulation (effect) of CGP-12177-labelled associated with antidepressant and fluoxetine
1) Confidence 0.06 Published 1996 Journal Brain Res. Bull. Section Abstract Doc Link 8879672 Disease Relevance 0 Pain Relevance 0.35
The effects of Ang II, losartan and CGP42,112A on nociception were measured using the tail flick test and the model of incision allodynia.
Regulation (effects) of CGP42 in tail associated with nociception, allodynia and tail-flick
2) Confidence 0.01 Published 2005 Journal Neuroscience Section Abstract Doc Link 15802196 Disease Relevance 1.25 Pain Relevance 0.80

General Comments

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