INT65909

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Context Info
Confidence 0.00
First Reported 1996
Last Reported 1996
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.45

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Golgi apparatus (GANAB) endoplasmic reticulum (GANAB) carbohydrate metabolic process (GANAB)
enzyme binding (LAMB1) protein folding (GANAB) extracellular space (LAMB1)
LAMB1 (Homo sapiens)
GANAB (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 8 99.06 Very High Very High Very High
local anesthetic 2 82.04 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings indicate that the beta 1 subunit is not required for the binding of sodium channel activators or inhibitors but rather, that the beta 1 subunit may stabilize the alpha subunit in a functional conformation thereby allowing detection of these interactions in disrupted membranes.
beta 1 subunit Spec (may) Positive_regulation (stabilize) of alpha subunit associated with sodium channel
1) Confidence 0.00 Published 1996 Journal Neuropharmacology Section Abstract Doc Link 8887969 Disease Relevance 0 Pain Relevance 0.45

General Comments

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