INT65962

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.07
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 0.89
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (NOX1) oxidoreductase activity (NOX1) plasma membrane (NOX1)
response to stress (NOX1)
Anatomy Link Frequency
plasma 1
myeloid cell 1
NOX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 6 99.58 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 16 99.76 Very High Very High Very High
Hyperplasia 2 96.52 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We now show that the vanilloids capsaicin, dihydrocapsaicin, and resiniferatoxin are inhibitors of the NADH-oxidase activity of the PMOR system and that both these and two previously identified PMOR inhibitors (chloroquine and retinoic acid) induce apoptosis in human B-cell and mouse myeloid cell lines.
Negative_regulation (inhibitors) of NADH-oxidase in myeloid cell associated with qutenza and apoptosis
1) Confidence 0.07 Published 1996 Journal Cell Growth Differ. Section Abstract Doc Link 8891335 Disease Relevance 0.41 Pain Relevance 0.10
Apoptosis induced by inhibitors of the plasma membrane NADH-oxidase involves Bcl-2 and calcineurin.
Negative_regulation (inhibitors) of NADH-oxidase in plasma associated with qutenza
2) Confidence 0.05 Published 1996 Journal Cell Growth Differ. Section Title Doc Link 8891335 Disease Relevance 0.48 Pain Relevance 0.29

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox