INT66002

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Context Info
Confidence 0.47
First Reported 1996
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 10
Disease Relevance 4.50
Pain Relevance 2.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (LAMC2) extracellular region (LAMC2) cell adhesion (LAMC2)
Anatomy Link Frequency
CSF 5
neurons 1
brain 1
LAMC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
transdermal 1 99.80 Very High Very High Very High
Migraine 2 99.68 Very High Very High Very High
headache 33 99.64 Very High Very High Very High
Clonidine 8 99.16 Very High Very High Very High
imagery 28 98.84 Very High Very High Very High
epidural 2 96.60 Very High Very High Very High
Neuropeptide 1 92.16 High High
Multiple sclerosis 2 91.08 High High
Central nervous system 1 86.08 High High
anesthesia 2 84.04 Quite High
Disease Link Frequency Relevance Heat
Metastasis 6 100.00 Very High Very High Very High
Leukocytosis 7 99.96 Very High Very High Very High
Pressure Volume 2 Under Development 5 99.92 Very High Very High Very High
Headache 28 99.68 Very High Very High Very High
Volume Depletion And Dehydration 1 99.44 Very High Very High Very High
Cyst 5 99.22 Very High Very High Very High
Neuropathy 1 98.44 Very High Very High Very High
Convulsion 30 93.56 High High
Herpes Simplex Encephalitis 2 93.08 High High
Myoclonus 2 92.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Paradoxical postural headache is yet another headache type that can be associated with CSF leak and CSF volume depletion.
CSF Binding (associated) of in CSF associated with volume depletion and dehydration and headache
1) Confidence 0.47 Published 2004 Journal Cephalalgia Section Abstract Doc Link 15377320 Disease Relevance 0.55 Pain Relevance 0.50
Migraine is usually not associated with CSF pleocytosis.
CSF Binding (associated) of associated with migraine and leukocytosis
2) Confidence 0.47 Published 2003 Journal Rinsho Shinkeigaku Section Abstract Doc Link 12820544 Disease Relevance 0.85 Pain Relevance 0.37
The possibility of acceleration of cerebrospinal fluid absorption in the sacral cyst was proposed for the cause of CSFH if CSF leakage was denied.
CSF Binding (leakage) of in cerebrospinal fluid associated with pressure volume 2 under development and cyst
3) Confidence 0.36 Published 2008 Journal Masui Section Abstract Doc Link 18975542 Disease Relevance 0.81 Pain Relevance 0.03
Nonetheless, DDE is most frequently associated with metastatic malignancies and particularly with skull metastases and CSF leak.
CSF Binding (associated) of in CSF associated with metastasis
4) Confidence 0.36 Published 1996 Journal J. Neurosurg. Section Abstract Doc Link 8893714 Disease Relevance 0.96 Pain Relevance 0.16
The mean of the serial CSF CRF concentrations exhibited a significant inverse relationship towards the GH response to clonidine in young adulthood, with relatively high CSF CRF associated with relatively attenuated GH responses to clonidine.
CSF Binding (associated) of in CSF associated with clonidine
5) Confidence 0.36 Published 2000 Journal Psychiatry Res Section Abstract Doc Link 10963795 Disease Relevance 0.05 Pain Relevance 0.81
Spontaneous CSF leaks are increasingly recognized, and a broader clinical and imaging spectrum of the disorder is emerging.
CSF Binding (recognized) of associated with imagery
6) Confidence 0.35 Published 2002 Journal Cephalalgia Section Abstract Doc Link 12485202 Disease Relevance 0.45 Pain Relevance 0.50
The type of anesthetic agent, patient's sex, or status (based on the American Society of Anesthesiology physical status and classification system), and presence of cardiopulmonary disease or seizure disorder were not associated with CSF hyperintensity.
CSF Binding (associated) of in CSF
7) Confidence 0.35 Published 2002 Journal AJR Am J Roentgenol Section Body Doc Link 12185066 Disease Relevance 0 Pain Relevance 0
A novel polymethylmethacrylate hydrophilic adhesive matrix intended for transdermal patch formulations.
adhesive Binding (intended) of associated with transdermal
8) Confidence 0.17 Published 2010 Journal Drug Deliv Section Title Doc Link 20210561 Disease Relevance 0 Pain Relevance 0.13
(A) NMDAR-antibody-positive CSF shows a hippocampal ‘neuropil’ binding pattern on rat brain sections.
CSF Binding (binding) of in brain
9) Confidence 0.11 Published 2010 Journal Brain Section Body Doc Link PMC2877907 Disease Relevance 0.82 Pain Relevance 0.05
To confirm the neuronal cell surface specificity of the antibodies and, thus, their likely clinical relevance, we incubated primary cultures of hippocampal neurons with sera and CSF to observe binding to the surface of live neurons (Fig. 1B).
CSF Binding (binding) of in neurons
10) Confidence 0.10 Published 2010 Journal Brain Section Body Doc Link PMC2877907 Disease Relevance 0 Pain Relevance 0

General Comments

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