INT66035

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Context Info
Confidence 0.00
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (FOLR2, Il1a) cytosol (Il1a) extracellular space (Il1a)
plasma membrane (FOLR2)
Anatomy Link Frequency
cartilage 1
FOLR2 (Homo sapiens)
Il1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 1 95.36 Very High Very High Very High
cINOD 1 93.24 High High
cytokine 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Cancer 1 100.00 Very High Very High Very High
Necrosis 1 99.96 Very High Very High Very High
Arthritis 2 96.72 Very High Very High Very High
INFLAMMATION 1 94.20 High High
Disease 1 92.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OBJECTIVE: We evaluated the effect of FR133605, a novel inhibitor of interleukin 1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha), on bone and cartilage destruction in adjuvant arthritic rats and compared it to corticosteroid, nonsteroidal antiinflammatory drugs (NSAID), and disease modifying antirheumatic drugs (DMARD).
FR133605 Negative_regulation (inhibitor) of IL-1 in cartilage associated with necrosis, corticosteroid, inflammation, cancer, cinod, disease and arthritis
1) Confidence 0.00 Published 1996 Journal J. Rheumatol. Section Abstract Doc Link 8895158 Disease Relevance 0.56 Pain Relevance 0.18

General Comments

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